Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1386878..1388411 Replicon chromosome
Accession NZ_LR536450
Organism Methylocella tundrae isolate MTUNDRAET4 annotated

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag MTUNDRAET4_RS06590 Protein ID WP_134488443.1
Coordinates 1386878..1387801 (-) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag MTUNDRAET4_RS06595 Protein ID WP_134488445.1
Coordinates 1387791..1388411 (-) Length 207 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTUNDRAET4_RS06555 1382785..1383551 + 767 WP_134488438.1 IS5 family transposase -
MTUNDRAET4_RS06560 1383567..1383989 - 423 Protein_1293 transposase -
MTUNDRAET4_RS06565 1384400..1384606 - 207 WP_134488439.1 hypothetical protein -
MTUNDRAET4_RS06575 1384824..1385480 + 657 WP_134488441.1 SDR family NAD(P)-dependent oxidoreductase -
MTUNDRAET4_RS06580 1385690..1385953 + 264 WP_197732023.1 DUF1778 domain-containing protein -
MTUNDRAET4_RS06585 1386100..1386450 + 351 WP_134492383.1 hypothetical protein -
MTUNDRAET4_RS06590 1386878..1387801 - 924 WP_134488443.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
MTUNDRAET4_RS06595 1387791..1388411 - 621 WP_134488445.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
MTUNDRAET4_RS06600 1388569..1389294 - 726 WP_166795885.1 M48 family metallopeptidase -
MTUNDRAET4_RS06605 1389303..1390832 - 1530 Protein_1301 DUF3387 domain-containing protein -
MTUNDRAET4_RS06610 1390829..1391476 - 648 Protein_1302 ParB/RepB/Spo0J family partition protein -
MTUNDRAET4_RS06615 1391779..1392213 - 435 WP_197731955.1 DUF4260 domain-containing protein -
MTUNDRAET4_RS06620 1392299..1393195 + 897 WP_134488449.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(39-258)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(22-55)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34168.13 Da        Isoelectric Point: 4.8849

>T288419 WP_134488443.1 NZ_LR536450:c1387801-1386878 [Methylocella tundrae]
MAHEPRKNVGASVRARLLDRSRVKRTDFQILLTRYALERLLYRLSLSLHRDRFILKGAMLFVTWVADPFRPTRDLDFLGY
GENSPEAIGEVFQEICGQPVDDDGVVFDIGAITAVPIREDVEYGGIRVRTSATIAGARIPIQVDIGFGDAVTPGPVEIVY
PPLLDAPAPHLRAYPVTTVVAEKFQALVLLGIANSRLKDFYDLWLIAQTFEFDRASLAEAVRQTFMRRGTMLPIEKPTGL
SDAYAEAWGRQWQAFLGRERMAAAPAELAVVVSDLAEFLLPLIEPAEGDERWKPSEGWRASDAGQDA

Download         Length: 924 bp

Antitoxin


Download         Length: 207 a.a.        Molecular weight: 22729.42 Da        Isoelectric Point: 10.1007

>AT288419 WP_134488445.1 NZ_LR536450:c1388411-1387791 [Methylocella tundrae]
MTQMDSQRAQALKLLKACPMMRLKDFAAHGIGPETLARLVRDGAVVRPARGLYQLADSSGNAARILAEASALVPKGVICL
ISALQFHELTLQMPSAVWMAIDRTAWRPKIDYPPIRFVRFTGSSLTDGVERHSIEGIEVAITSPARTIVDCFRYRAKVGL
DVALEGLREGLRQRKVTSDQLWTYGTKGKVWSTMRPYVEATVADGT

Download         Length: 621 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References