Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1386878..1388411 Replicon chromosome
Accession NZ_LR536450
Organism Methylocella tundrae isolate MTUNDRAET4 annotated

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag MTUNDRAET4_RS06590 Protein ID WP_134488443.1
Coordinates 1386878..1387801 (-) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag MTUNDRAET4_RS06595 Protein ID WP_134488445.1
Coordinates 1387791..1388411 (-) Length 207 a.a.

Genomic Context

MTUNDRAET4_RS06555MTUNDRAET4_RS06575MTUNDRAET4_RS06580MTUNDRAET4_RS06585MTUNDRAET4_RS06620MTUNDRAET4_RS06560MTUNDRAET4_RS06565MTUNDRAET4_RS06590MTUNDRAET4_RS06595MTUNDRAET4_RS06600MTUNDRAET4_RS06605MTUNDRAET4_RS06610MTUNDRAET4_RS06615
Location: 1382785..1383551 (767 bp)
Type: Others
Protein ID: WP_134488438.1
Location: 1384824..1385480 (657 bp)
Type: Others
Protein ID: WP_134488441.1
Location: 1385690..1385953 (264 bp)
Type: Others
Protein ID: WP_197732023.1
Location: 1386100..1386450 (351 bp)
Type: Others
Protein ID: WP_134492383.1
Location: 1392299..1393195 (897 bp)
Type: Others
Protein ID: WP_134488449.1
Location: 1383567..1383989 (423 bp)
Type: Others
Protein ID: Protein_1293
Location: 1384400..1384606 (207 bp)
Type: Others
Protein ID: WP_134488439.1
Location: 1386878..1387801 (924 bp)
Type: Toxin
Protein ID: WP_134488443.1
Location: 1387791..1388411 (621 bp)
Type: Antitoxin
Protein ID: WP_134488445.1
Location: 1388569..1389294 (726 bp)
Type: Others
Protein ID: WP_166795885.1
Location: 1389303..1390832 (1530 bp)
Type: Others
Protein ID: Protein_1301
Location: 1390829..1391476 (648 bp)
Type: Others
Protein ID: Protein_1302
Location: 1391779..1392213 (435 bp)
Type: Others
Protein ID: WP_197731955.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MTUNDRAET4_RS065551382785..1383551+767WP_134488438.1IS5 family transposase-
MTUNDRAET4_RS065601383567..1383989-423Protein_1293transposase-
MTUNDRAET4_RS065651384400..1384606-207WP_134488439.1hypothetical protein-
MTUNDRAET4_RS065751384824..1385480+657WP_134488441.1SDR family NAD(P)-dependent oxidoreductase-
MTUNDRAET4_RS065801385690..1385953+264WP_197732023.1DUF1778 domain-containing protein-
MTUNDRAET4_RS065851386100..1386450+351WP_134492383.1hypothetical protein-
MTUNDRAET4_RS065901386878..1387801-924WP_134488443.1nucleotidyl transferase AbiEii/AbiGii toxin family proteinToxin
MTUNDRAET4_RS065951387791..1388411-621WP_134488445.1type IV toxin-antitoxin system AbiEi family antitoxin domain-containing proteinAntitoxin
MTUNDRAET4_RS066001388569..1389294-726WP_166795885.1M48 family metallopeptidase-
MTUNDRAET4_RS066051389303..1390832-1530Protein_1301DUF3387 domain-containing protein-
MTUNDRAET4_RS066101390829..1391476-648Protein_1302ParB/RepB/Spo0J family partition protein-
MTUNDRAET4_RS066151391779..1392213-435WP_197731955.1DUF4260 domain-containing protein-
MTUNDRAET4_RS066201392299..1393195+897WP_134488449.1LysR family transcriptional regulator-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(39-258)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(22-55)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34168.13 Da        Isoelectric Point: 4.8849

>T288419 WP_134488443.1 NZ_LR536450:c1387801-1386878 [Methylocella tundrae]
MAHEPRKNVGASVRARLLDRSRVKRTDFQILLTRYALERLLYRLSLSLHRDRFILKGAMLFVTWVADPFRPTRDLDFLGY
GENSPEAIGEVFQEICGQPVDDDGVVFDIGAITAVPIREDVEYGGIRVRTSATIAGARIPIQVDIGFGDAVTPGPVEIVY
PPLLDAPAPHLRAYPVTTVVAEKFQALVLLGIANSRLKDFYDLWLIAQTFEFDRASLAEAVRQTFMRRGTMLPIEKPTGL
SDAYAEAWGRQWQAFLGRERMAAAPAELAVVVSDLAEFLLPLIEPAEGDERWKPSEGWRASDAGQDA

Download         Length: 924 bp

Antitoxin


Download         Length: 207 a.a.        Molecular weight: 22729.42 Da        Isoelectric Point: 10.1007

>AT288419 WP_134488445.1 NZ_LR536450:c1388411-1387791 [Methylocella tundrae]
MTQMDSQRAQALKLLKACPMMRLKDFAAHGIGPETLARLVRDGAVVRPARGLYQLADSSGNAARILAEASALVPKGVICL
ISALQFHELTLQMPSAVWMAIDRTAWRPKIDYPPIRFVRFTGSSLTDGVERHSIEGIEVAITSPARTIVDCFRYRAKVGL
DVALEGLREGLRQRKVTSDQLWTYGTKGKVWSTMRPYVEATVADGT

Download         Length: 621 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References