Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2164973..2165244 Replicon chromosome
Accession NZ_LR536431
Organism Escherichia coli isolate f9610206-5e81-11e8-bf7f-3c4a9275d6c8

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2165103..2165206 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2164973..2165244 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4Z82_RS10660 2161528..2162190 - 663 WP_000944266.1 exodeoxyribonuclease X -
E4Z82_RS10665 2162214..2162870 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
E4Z82_RS10670 2162972..2163202 - 231 WP_000916763.1 DNA polymerase III subunit theta -
E4Z82_RS10675 2163341..2163715 + 375 WP_000168747.1 CopC domain-containing protein YobA -
E4Z82_RS10680 2163719..2164591 + 873 WP_000879301.1 copper homeostasis membrane protein CopD -
E4Z82_RS10685 2164604..2164945 + 342 WP_000976476.1 YebY family protein -
- 2164973..2165244 - 272 - - Antitoxin
- 2165103..2165206 + 104 - - Toxin
E4Z82_RS10690 2165341..2165997 + 657 WP_000812734.1 protein-serine/threonine phosphatase -
E4Z82_RS10695 2165998..2166189 - 192 WP_001296140.1 YebW family protein -
E4Z82_RS10700 2166294..2166530 - 237 WP_001295499.1 DUF1480 family protein -
E4Z82_RS10705 2166648..2168087 - 1440 WP_024226338.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2091322..2186176 94854


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T288409 NZ_LR536431:2165103-2165206 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT288409 NZ_LR536431:c2165244-2164973 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References