Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3186487..3186758 Replicon chromosome
Accession NZ_LR217818
Organism Escherichia coli strain NCTC86

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3186525..3186628 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3186487..3186758 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4V11_RS15705 3183644..3185083 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
E4V11_RS15710 3185201..3185437 + 237 WP_001295499.1 DUF1480 family protein -
E4V11_RS15715 3185542..3185733 + 192 WP_000457842.1 YebW family protein -
E4V11_RS15720 3185734..3186390 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 3186487..3186758 + 272 - - Antitoxin
- 3186525..3186628 - 104 - - Toxin
E4V11_RS15725 3186786..3187127 - 342 WP_000976476.1 YebY family protein -
E4V11_RS15730 3187140..3188012 - 873 WP_066009214.1 copper homeostasis membrane protein CopD -
E4V11_RS15735 3188016..3188390 - 375 WP_000168747.1 CopC domain-containing protein YobA -
E4V11_RS15740 3188529..3188759 + 231 WP_000916763.1 DNA polymerase III subunit theta -
E4V11_RS15745 3188861..3189517 + 657 WP_066009212.1 carbon-nitrogen hydrolase family protein -
E4V11_RS15750 3189541..3190203 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T288362 NZ_LR217818:c3186628-3186525 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT288362 NZ_LR217818:3186487-3186758 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References