Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 132057..132546 Replicon chromosome
Accession NZ_LR215983
Organism Eubacterium limosum isolate Eubacterium limosum 81C1

Toxin (Protein)


Gene name relE Uniprot ID A0A317S0V5
Locus tag E4L76_RS00620 Protein ID WP_038352201.1
Coordinates 132271..132546 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A317RXL4
Locus tag E4L76_RS00615 Protein ID WP_038352202.1
Coordinates 132057..132278 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4L76_RS22455 127360..127512 + 153 WP_172610829.1 hypothetical protein -
E4L76_RS00595 127652..128146 + 495 WP_133964511.1 hypothetical protein -
E4L76_RS00600 128177..129670 - 1494 WP_133964512.1 glycerol kinase GlpK -
E4L76_RS00605 129682..131217 - 1536 WP_133964513.1 amidohydrolase -
E4L76_RS00610 131222..131797 - 576 WP_167617886.1 glycerol-3-phosphate responsive antiterminator -
E4L76_RS00615 132057..132278 + 222 WP_038352202.1 ribbon-helix-helix protein, CopG family Antitoxin
E4L76_RS00620 132271..132546 + 276 WP_038352201.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
E4L76_RS00625 132667..136038 + 3372 WP_133964514.1 exodeoxyribonuclease V subunit gamma -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-89)

Antitoxin

Protein of unknown function DUF6290

(1-70)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10646.43 Da        Isoelectric Point: 10.1275

>T288328 WP_038352201.1 NZ_LR215983:132271-132546 [Eubacterium limosum]
MAEKYHVVLTEKAKKSLKKLDKHTALLITAWLRKNLEGCTDPYQYGKGLTANRSGQWRYRIGDYRLVCEISEQTITILVL
NIGHRKEIYKH

Download         Length: 276 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8523.66 Da        Isoelectric Point: 4.1285

>AT288328 WP_038352202.1 NZ_LR215983:132057-132278 [Eubacterium limosum]
MAVSLRLNKEDEALIRSYAEMKNLSVSEAIRQAIMEKIEDEFDLKVYYEAMTEYKENPVTYTLDEVERELGLG

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A317S0V5

Antitoxin

Source ID Structure
AlphaFold DB A0A317RXL4

References