Detailed information of TA system TA288319

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/RHH(antitoxin)
• Location: 2392994..2393547
• Replicon: chromosome
• Accession: NZ_LR215729
• Organism: Pseudomonas marincola strain YSy11

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: PMYSY11_RS11115
• Protein ID: WP_150549224.1
• Coordinates: 2392994..2393287 (-)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: PMYSY11_RS11120
• Protein ID: WP_116801393.1
• Coordinates: 2393275..2393547 (-)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PMYSY11_RS11100	2389121..2390806	-	1686	WP_150549222.1	GMC family oxidoreductase	-
PMYSY11_RS11105	2391156..2391293	-	138	WP_172970686.1	hypothetical protein	-
PMYSY11_RS11110	2391591..2393000	+	1410	WP_150549223.1	site-specific integrase	-
PMYSY11_RS11115	2392994..2393287	-	294	WP_150549224.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
PMYSY11_RS11120	2393275..2393547	-	273	WP_116801393.1	CopG family ribbon-helix-helix protein	Antitoxin
PMYSY11_RS11125	2393949..2394281	+	333	WP_036992178.1	hypothetical protein	-
PMYSY11_RS11130	2394341..2395309	+	969	WP_150549225.1	DUF932 domain-containing protein	-
PMYSY11_RS11135	2395393..2395797	-	405	WP_150549226.1	tRNA(fMet)-specific endonuclease VapC	-
PMYSY11_RS11140	2395797..2396027	-	231	WP_003285520.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	-
PMYSY11_RS11145	2396184..2397188	+	1005	WP_150549227.1	YqaJ viral recombinase family protein	-
PMYSY11_RS11150	2397280..2398230	+	951	WP_150549228.1	hydrolase or metal-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2389121..2399979	10858

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-95)

Antitoxin

• Ribbon-helix-helix protein, CopG (3-40)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 11125.63 Da
• Isoelectric Point: 6.9818

>T288319 WP_150549224.1 NZ_LR215729:c2393287-2392994 [Pseudomonas marincola]
VPRLIVTEGAAKGLERCRRFLSDKDPQVARRAAQAIERQFARLEESPEVGRPFPDLPELRVLIIEFGDSGYVALYRYERA
DDTAYVLAFRHQKEAGY

Nucleotide

• Length: 294 bp

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 10523.65 Da
• Isoelectric Point: 5.6460

>AT288319 WP_116801393.1 NZ_LR215729:c2393547-2393275 [Pseudomonas marincola]
MATSIKIDDELKGRIQQLASQRQRSSHWIMREAITQYVEREEARESFKQEALASWAAYQETGRHLTSQETRTWLGSWGTD
TEVELPKCHD

Nucleotide

• Length: 273 bp