Detailed information of TA system TA288318

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Acetyltransf_4(toxin)
• Location: 1707121..1708537
• Replicon: chromosome
• Accession: NZ_LR215729
• Organism: Pseudomonas marincola strain YSy11

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: PMYSY11_RS08025
• Protein ID: WP_069901713.1
• Coordinates: 1707121..1707690 (+)
• Length: 190 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: PMYSY11_RS08030
• Protein ID: WP_150548841.1
• Coordinates: 1707698..1708537 (+)
• Length: 280 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PMYSY11_RS08020	1703374..1706856	-	3483	WP_150548840.1	hybrid sensor histidine kinase/response regulator	-
PMYSY11_RS08025	1707121..1707690	+	570	WP_069901713.1	GNAT family N-acetyltransferase	Toxin
PMYSY11_RS08030	1707698..1708537	+	840	WP_150548841.1	AraC family transcriptional regulator	Antitoxin
PMYSY11_RS08035	1708625..1709335	+	711	WP_150548842.1	AzlC family ABC transporter permease	-
PMYSY11_RS08040	1709335..1709664	+	330	WP_150548843.1	AzlD domain-containing protein	-
PMYSY11_RS08045	1709814..1711688	+	1875	WP_150548844.1	MFS transporter	-
PMYSY11_RS08050	1712172..1712486	-	315	WP_069901718.1	quaternary ammonium compound efflux SMR transporter SugE	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (14-146)

Antitoxin

• DNA binding HTH domain, AraC-type (194-271)

Sequences

Toxin

Protein

• Length: 190 a.a.
• Molecular weight: 21419.76 Da
• Isoelectric Point: 9.7273

>T288318 WP_069901713.1 NZ_LR215729:1707121-1707690 [Pseudomonas marincola]
MFKPQLITLQRGALRIEPMMDADIPALVSLAEANRNELIYMGGAQRLDWYRQGIVEQQNSRALPFTIRLGTEIVGTTRYA
DFMPTLPACEIGWTWLDKGQHGTGLNSMIKYLMLRHAFEGWRMVRVQLKTAASNLRAQAAIEKIGAQREGILRNHRRLSE
GRLDDSVLYSITDQEWPAVKKMIESGFGG

Nucleotide

• Length: 570 bp

Antitoxin

Protein

• Length: 280 a.a.
• Molecular weight: 30884.17 Da
• Isoelectric Point: 9.6547

>AT288318 WP_150548841.1 NZ_LR215729:1707698-1708537 [Pseudomonas marincola]
MNEALEQTRFWQAKGLADVELLHARYVQQRFAPHVHEGFVFTVIQNGAQRFRHRGSDHLAPQGSMVLINPDEVHTGSKAH
DDGWRYRAFYPDNRQVQGVLQELDLAGSGLPGFALSVLHDPQLHAAFTGLHQLLEGGADALQQQIVWREAILLLFQRYAK
VAEPAAPGREARAVELAKELLNSQLAAPPSLEELATAVNLSPFHFARVFRRATGLPPHAWLKQRRLAQARALLKQGCMPA
QVAMQLGFSDQSHLSRQFKQVYGVGPGAYRNASAGIASL

Nucleotide

• Length: 840 bp