Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2086022..2086256 | Replicon | chromosome |
| Accession | NZ_LR213455 | ||
| Organism | Shigella flexneri strain AUSMDU00008332 isolate AUSMDU00008332 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2086152..2086255 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2086022..2086256 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E0E35_RS10700 | 2082577..2083239 | - | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
| E0E35_RS10705 | 2083263..2083919 | - | 657 | Protein_2026 | carbon-nitrogen hydrolase family protein | - |
| E0E35_RS10710 | 2084021..2084251 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| E0E35_RS10715 | 2084390..2084764 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| E0E35_RS10720 | 2084768..2085640 | + | 873 | Protein_2029 | copper homeostasis membrane protein CopD | - |
| E0E35_RS10725 | 2085653..2085994 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 2086022..2086256 | - | 235 | - | - | Antitoxin |
| - | 2086152..2086255 | + | 104 | - | - | Toxin |
| E0E35_RS26380 | 2086387..2087464 | - | 1078 | Protein_2031 | phage integrase Arm DNA-binding domain-containing protein | - |
| E0E35_RS10740 | 2087430..2087711 | - | 282 | WP_005127484.1 | excisionase | - |
| E0E35_RS10745 | 2087828..2088676 | - | 849 | Protein_2033 | IS3-like element IS600 family transposase | - |
| E0E35_RS10750 | 2088731..2089926 | + | 1196 | Protein_2034 | IS3 family transposase | - |
| E0E35_RS10755 | 2089969..2090279 | - | 311 | Protein_2035 | transposase | - |
| E0E35_RS10760 | 2090343..2090810 | + | 468 | Protein_2036 | DNA-binding transcriptional regulator PgrR | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T288270 NZ_LR213455:2086152-2086255 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT288270 NZ_LR213455:c2086256-2086022 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
