Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | Txe-Axe/Txe-RelB |
Location | 36703..37222 | Replicon | plasmid 3 |
Accession | NZ_LR135477 | ||
Organism | Enterococcus faecium isolate E8423 |
Toxin (Protein)
Gene name | Txe | Uniprot ID | Q848U6 |
Locus tag | EQB52_RS15545 | Protein ID | WP_000588503.1 |
Coordinates | 36965..37222 (+) | Length | 86 a.a. |
Antitoxin (Protein)
Gene name | Axe | Uniprot ID | Q83WJ8 |
Locus tag | EQB52_RS15540 | Protein ID | WP_000388479.1 |
Coordinates | 36703..36972 (+) | Length | 90 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EQB52_RS15515 | 33242..34636 | + | 1395 | Protein_41 | type I restriction-modification system subunit M | - |
EQB52_RS15520 | 34691..35371 | - | 681 | WP_001015311.1 | IS6-like element IS1216 family transposase | - |
EQB52_RS15525 | 35447..36013 | + | 567 | Protein_43 | hypothetical protein | - |
EQB52_RS15535 | 36393..36572 | + | 180 | WP_001120991.1 | hypothetical protein | - |
EQB52_RS15540 | 36703..36972 | + | 270 | WP_000388479.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
EQB52_RS15545 | 36965..37222 | + | 258 | WP_000588503.1 | Txe/YoeB family addiction module toxin | Toxin |
EQB52_RS15550 | 37860..38684 | + | 825 | WP_001809248.1 | hypothetical protein | - |
EQB52_RS15555 | 38849..39463 | - | 615 | WP_001261742.1 | recombinase family protein | - |
EQB52_RS15560 | 39913..41238 | + | 1326 | WP_000969590.1 | Y-family DNA polymerase | - |
EQB52_RS15565 | 41231..41581 | + | 351 | WP_000568378.1 | hypothetical protein | - |
EQB52_RS15570 | 41578..41757 | + | 180 | WP_001021554.1 | hypothetical protein | - |
EQB52_RS15575 | 41893..42183 | + | 291 | WP_000026576.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | erm(B) / aph(3')-III / VanHAX | - | 1..44000 | 44000 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A828ZXQ8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A828ZWU7 |