Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relE-yefM/Txe-RelB |
Location | 460538..461067 | Replicon | chromosome |
Accession | NZ_LR135475 | ||
Organism | Enterococcus faecium isolate E8423 |
Toxin (Protein)
Gene name | relE | Uniprot ID | Q3XX67 |
Locus tag | EQB52_RS02335 | Protein ID | WP_002296560.1 |
Coordinates | 460538..460804 (-) | Length | 89 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | A0A829F3T0 |
Locus tag | EQB52_RS02340 | Protein ID | WP_002296559.1 |
Coordinates | 460804..461067 (-) | Length | 88 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EQB52_RS02305 | 455938..456342 | - | 405 | WP_002287522.1 | IS200/IS605-like element ISEfa4 family transposase | - |
EQB52_RS02310 | 456500..457081 | + | 582 | Protein_415 | CBS domain-containing protein | - |
EQB52_RS02315 | 457085..457726 | + | 642 | WP_002293405.1 | ABC transporter permease | - |
EQB52_RS02320 | 457723..458640 | + | 918 | WP_002296564.1 | osmoprotectant ABC transporter substrate-binding protein | - |
EQB52_RS02325 | 458637..459308 | + | 672 | WP_002302663.1 | ABC transporter permease | - |
EQB52_RS02330 | 459849..460337 | - | 489 | WP_002296561.1 | mannosyl-glycoprotein endo-beta-N-acetylglucosamidase | - |
EQB52_RS02335 | 460538..460804 | - | 267 | WP_002296560.1 | Txe/YoeB family addiction module toxin | Toxin |
EQB52_RS02340 | 460804..461067 | - | 264 | WP_002296559.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
EQB52_RS02350 | 461543..461728 | + | 186 | WP_002296558.1 | transcriptional regulator | - |
EQB52_RS02355 | 461870..463693 | - | 1824 | WP_002294202.1 | APC family permease | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A829FCW8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A829F3T0 |