Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relE-yefM/Txe-RelB |
Location | 200235..200764 | Replicon | chromosome |
Accession | NZ_LR135419 | ||
Organism | Enterococcus faecium isolate E8440 |
Toxin (Protein)
Gene name | relE | Uniprot ID | Q3XX67 |
Locus tag | FQ475_RS00985 | Protein ID | WP_002296560.1 |
Coordinates | 200498..200764 (+) | Length | 89 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | A0A829F3T0 |
Locus tag | FQ475_RS00980 | Protein ID | WP_002296559.1 |
Coordinates | 200235..200498 (+) | Length | 88 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FQ475_RS00970 | 197609..199432 | + | 1824 | WP_002294202.1 | APC family permease | - |
FQ475_RS00975 | 199574..199759 | - | 186 | WP_002296558.1 | transcriptional regulator | - |
FQ475_RS00980 | 200235..200498 | + | 264 | WP_002296559.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
FQ475_RS00985 | 200498..200764 | + | 267 | WP_002296560.1 | Txe/YoeB family addiction module toxin | Toxin |
FQ475_RS00990 | 200965..201453 | + | 489 | WP_002296561.1 | mannosyl-glycoprotein endo-beta-N-acetylglucosamidase | - |
FQ475_RS00995 | 201994..202665 | - | 672 | WP_002302663.1 | ABC transporter permease | - |
FQ475_RS01000 | 202662..203579 | - | 918 | WP_002302664.1 | osmoprotectant ABC transporter substrate-binding protein | - |
FQ475_RS01005 | 203576..204217 | - | 642 | WP_002293405.1 | ABC transporter permease | - |
FQ475_RS01010 | 204221..205396 | - | 1176 | WP_002294192.1 | betaine/proline/choline family ABC transporter ATP-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A829FCW8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A829F3T0 |