Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | Txe-Axe/Txe-RelB |
Location | 48395..48914 | Replicon | plasmid 3 |
Accession | NZ_LR135326 | ||
Organism | Enterococcus faecium isolate E7654 |
Toxin (Protein)
Gene name | Txe | Uniprot ID | Q848U6 |
Locus tag | EQB39_RS15605 | Protein ID | WP_000588503.1 |
Coordinates | 48657..48914 (+) | Length | 86 a.a. |
Antitoxin (Protein)
Gene name | Axe | Uniprot ID | Q83WJ8 |
Locus tag | EQB39_RS15600 | Protein ID | WP_000388479.1 |
Coordinates | 48395..48664 (+) | Length | 90 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EQB39_RS15545 | 43592..44491 | + | 900 | WP_002303312.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
EQB39_RS15550 | 44494..44979 | + | 486 | WP_002303313.1 | single-stranded DNA-binding protein | - |
EQB39_RS15555 | 45120..45323 | - | 204 | WP_002316074.1 | putative holin-like toxin | - |
EQB39_RS15560 | 45398..45658 | + | 261 | WP_002295623.1 | hypothetical protein | - |
EQB39_RS15570 | 46095..46301 | + | 207 | WP_002347218.1 | hypothetical protein | - |
EQB39_RS15575 | 46301..46552 | + | 252 | WP_002296238.1 | hypothetical protein | - |
EQB39_RS15580 | 46567..47004 | + | 438 | WP_002300851.1 | hypothetical protein | - |
EQB39_RS15585 | 46997..47704 | + | 708 | WP_002303117.1 | hypothetical protein | - |
EQB39_RS15595 | 48085..48264 | + | 180 | WP_001120991.1 | hypothetical protein | - |
EQB39_RS15600 | 48395..48664 | + | 270 | WP_000388479.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
EQB39_RS15605 | 48657..48914 | + | 258 | WP_000588503.1 | Txe/YoeB family addiction module toxin | Toxin |
EQB39_RS16245 | 49373..49528 | + | 156 | WP_002347142.1 | hypothetical protein | - |
EQB39_RS15610 | 49552..50376 | + | 825 | WP_001809248.1 | hypothetical protein | - |
EQB39_RS15615 | 50541..51155 | - | 615 | WP_001261742.1 | recombinase family protein | - |
EQB39_RS15620 | 51393..51815 | + | 423 | WP_002303116.1 | hypothetical protein | - |
EQB39_RS15625 | 51825..52028 | + | 204 | WP_002299573.1 | hypothetical protein | - |
EQB39_RS15630 | 52240..52824 | + | 585 | WP_002299575.1 | recombinase family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..61971 | 61971 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A828ZXQ8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A828ZWU7 |