Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | Txe-Axe/Txe-RelB |
Location | 8731..9250 | Replicon | plasmid 3 |
Accession | NZ_LR135176 | ||
Organism | Enterococcus faecium isolate E4402 |
Toxin (Protein)
Gene name | Txe | Uniprot ID | Q848U6 |
Locus tag | EL348_RS14670 | Protein ID | WP_000588503.1 |
Coordinates | 8993..9250 (+) | Length | 86 a.a. |
Antitoxin (Protein)
Gene name | Axe | Uniprot ID | Q83WJ8 |
Locus tag | EL348_RS14665 | Protein ID | WP_000388479.1 |
Coordinates | 8731..9000 (+) | Length | 90 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EL348_RS14625 | 5187..5549 | - | 363 | WP_002313294.1 | hypothetical protein | - |
EL348_RS14630 | 5553..5891 | - | 339 | WP_002305963.1 | hypothetical protein | - |
EL348_RS14635 | 5870..6289 | - | 420 | WP_002305964.1 | hypothetical protein | - |
EL348_RS14640 | 6286..6546 | - | 261 | Protein_7 | replication protein | - |
EL348_RS14645 | 6603..7283 | - | 681 | WP_001015311.1 | IS6-like element IS1216 family transposase | - |
EL348_RS14650 | 7345..8040 | + | 696 | WP_002326819.1 | hypothetical protein | - |
EL348_RS14660 | 8421..8600 | + | 180 | WP_001120991.1 | hypothetical protein | - |
EL348_RS14665 | 8731..9000 | + | 270 | WP_000388479.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
EL348_RS14670 | 8993..9250 | + | 258 | WP_000588503.1 | Txe/YoeB family addiction module toxin | Toxin |
EL348_RS14675 | 9709..10713 | + | 1005 | WP_000455809.1 | hypothetical protein | - |
EL348_RS14680 | 10878..11492 | - | 615 | WP_001261742.1 | recombinase family protein | - |
EL348_RS14685 | 11942..13267 | + | 1326 | WP_000969590.1 | Y-family DNA polymerase | - |
EL348_RS14690 | 13260..13610 | + | 351 | WP_000568378.1 | hypothetical protein | - |
EL348_RS14695 | 13607..13786 | + | 180 | WP_001021554.1 | hypothetical protein | - |
EL348_RS14700 | 13922..14212 | + | 291 | WP_000026576.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..16029 | 16029 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A828ZXQ8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A828ZWU7 |