Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | TsdAT/- |
Location | 1953056..1953565 | Replicon | chromosome |
Accession | NZ_LR134536 | ||
Organism | Staphylococcus epidermidis strain NCTC13924 |
Toxin (Protein)
Gene name | TsdT | Uniprot ID | Q5HMD5 |
Locus tag | EL299_RS09735 | Protein ID | WP_001829980.1 |
Coordinates | 1953056..1953265 (-) | Length | 70 a.a. |
Antitoxin (Protein)
Gene name | TsdA | Uniprot ID | Q5HMD4 |
Locus tag | EL299_RS09740 | Protein ID | WP_001829893.1 |
Coordinates | 1953272..1953565 (-) | Length | 98 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EL299_RS09715 | 1948634..1949989 | - | 1356 | WP_001832734.1 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase | - |
EL299_RS09720 | 1950001..1951074 | - | 1074 | WP_001832735.1 | D-alanine--D-alanine ligase | - |
EL299_RS09725 | 1951465..1952676 | + | 1212 | WP_001829910.1 | rod shape-determining protein RodA | - |
EL299_RS09730 | 1952776..1952913 | - | 138 | WP_001829949.1 | hypothetical protein | - |
EL299_RS09735 | 1953056..1953265 | - | 210 | WP_001829980.1 | heavy-metal-associated domain-containing protein | Toxin |
EL299_RS09740 | 1953272..1953565 | - | 294 | WP_001829893.1 | copper-sensing transcriptional repressor CsoR | Antitoxin |
EL299_RS09745 | 1953739..1955223 | + | 1485 | WP_002457116.1 | cardiolipin synthase | - |
EL299_RS09750 | 1955405..1956058 | + | 654 | WP_001829983.1 | HD domain-containing protein | - |
EL299_RS09755 | 1956164..1957036 | - | 873 | WP_002458703.1 | membrane protein insertase YidC | - |
EL299_RS09760 | 1957125..1957763 | - | 639 | WP_002505076.1 | thiamine phosphate synthase | - |
EL299_RS09765 | 1957769..1958557 | - | 789 | WP_001829971.1 | hydroxyethylthiazole kinase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2G7HWU1 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0N1EPA7 |