Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 3045633..3046293 Replicon chromosome
Accession NZ_LR134535
Organism Arachnia propionica strain NCTC11666

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EL396_RS13430 Protein ID WP_126379752.1
Coordinates 3045633..3046058 (-) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EL396_RS13435 Protein ID WP_126379754.1
Coordinates 3046045..3046293 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL396_RS13405 3041218..3041874 - 657 WP_126380550.1 response regulator transcription factor -
EL396_RS13410 3041868..3043055 - 1188 WP_126379744.1 histidine kinase -
EL396_RS13415 3043185..3043907 + 723 WP_126379746.1 ABC transporter ATP-binding protein -
EL396_RS13420 3043904..3044686 + 783 WP_126379748.1 hypothetical protein -
EL396_RS13425 3044836..3045354 - 519 WP_126379750.1 lincomycin resistance protein LmrB -
EL396_RS13430 3045633..3046058 - 426 WP_126379752.1 type II toxin-antitoxin system VapC family toxin Toxin
EL396_RS13435 3046045..3046293 - 249 WP_126379754.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
EL396_RS13440 3046565..3046804 + 240 WP_126379756.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
EL396_RS13445 3047302..3049062 + 1761 WP_126379758.1 ATP-binding cassette domain-containing protein -
EL396_RS13450 3049052..3050860 + 1809 WP_164723128.1 ABC transporter ATP-binding protein/permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 2998539..3051696 53157


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(2-139)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15714.11 Da        Isoelectric Point: 7.9341

>T288030 WP_126379752.1 NZ_LR134535:c3046058-3045633 [Arachnia propionica]
VLLADVNLFIYAHRPESPRFAEHHAWLTAALTADEPFGVSELILSGFLRIVTNHRVYREPTPPQVALDFCQTVLSAPSAV
RIRPGREHWRIFESLCRNLGARGNVVPDAYLAAMAIEAGATFITMDAGFARFPGLTWRRAL

Download         Length: 426 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8844.92 Da        Isoelectric Point: 4.8283

>AT288030 WP_126379754.1 NZ_LR134535:c3046293-3046045 [Arachnia propionica]
MRTTVNLDDELLRRAKERAARQGRTLSEVVSDALQVSLAEQAGPRREVTLPTFGGSGLKPGVDLEDKDALAALLGEDDRA
AR

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References