Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 2144746..2145311 Replicon chromosome
Accession NZ_LR134535
Organism Arachnia propionica strain NCTC11666

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag EL396_RS09330 Protein ID WP_126378484.1
Coordinates 2144746..2145093 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag EL396_RS09335 Protein ID WP_164723182.1
Coordinates 2145093..2145311 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL396_RS09325 2141650..2143680 + 2031 WP_126378482.1 hypothetical protein -
EL396_RS09330 2144746..2145093 - 348 WP_126378484.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
EL396_RS09335 2145093..2145311 - 219 WP_164723182.1 ribbon-helix-helix domain-containing protein Antitoxin
EL396_RS09340 2145458..2148241 - 2784 WP_126380493.1 vitamin B12-dependent ribonucleotide reductase -
EL396_RS09345 2148345..2148881 - 537 WP_014846985.1 transcriptional regulator NrdR -
EL396_RS09350 2149080..2149409 - 330 WP_126378487.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-112)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-37)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 12361.41 Da        Isoelectric Point: 11.5180

>T288026 WP_126378484.1 NZ_LR134535:c2145093-2144746 [Arachnia propionica]
VLRGEIRLVDLESALAGAADKRRPAVIVSNDRANTVAARLGRGVVTVVPITSNTARVFPFQVLLTADEVGIRLDSKAQAE
QVRAVPVDRIGPVIGRLPARLVAQLDEALRLHLQL

Download         Length: 348 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 7591.42 Da        Isoelectric Point: 4.0390

>AT288026 WP_164723182.1 NZ_LR134535:c2145311-2145093 [Arachnia propionica]
VKLSVSLSPSEVAVLDKYAQSAGLKSRSAAIQQAIKLLGDPDLEDAYTAAWQEWEDAGEAEAWAVTVADGAK

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References