Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prpT-prpA/ParE-CC2985
Location 1436721..1437270 Replicon chromosome
Accession NZ_LR134531
Organism Pragia fontium strain NCTC12284

Toxin (Protein)


Gene name PrpT Uniprot ID -
Locus tag EL341_RS06270 Protein ID WP_126467366.1
Coordinates 1436965..1437270 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name PrpA Uniprot ID A0A0G3CPL6
Locus tag EL341_RS06265 Protein ID WP_047780617.1
Coordinates 1436721..1436978 (+) Length 86 a.a.

Genomic Context

EL341_RS06265EL341_RS06270EL341_RS06280EL341_RS06250EL341_RS17655EL341_RS17660EL341_RS06260EL341_RS06275
Location: 1436721..1436978 (258 bp)
Type: Antitoxin
Protein ID: WP_047780617.1
Location: 1436965..1437270 (306 bp)
Type: Toxin
Protein ID: WP_126467366.1
Location: 1438947..1440137 (1191 bp)
Type: Others
Protein ID: WP_126467370.1
Location: 1432409..1433944 (1536 bp)
Type: Others
Protein ID: WP_126467362.1
Location: 1433952..1434830 (879 bp)
Type: Others
Protein ID: WP_047780614.1
Location: 1434849..1435322 (474 bp)
Type: Others
Protein ID: WP_047780615.1
Location: 1435335..1436390 (1056 bp)
Type: Others
Protein ID: WP_126467364.1
Location: 1437364..1438788 (1425 bp)
Type: Others
Protein ID: WP_126467368.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EL341_RS062501432409..1433944-1536WP_126467362.1apolipoprotein N-acyltransferase-
EL341_RS176551433952..1434830-879WP_047780614.1CNNM family magnesium/cobalt transport protein CorC-
EL341_RS176601434849..1435322-474WP_047780615.1rRNA maturation RNase YbeY-
EL341_RS062601435335..1436390-1056WP_126467364.1PhoH family protein-
EL341_RS062651436721..1436978+258WP_047780617.1type II toxin-antitoxin system ParD family antitoxinAntitoxin
EL341_RS062701436965..1437270+306WP_126467366.1type II toxin-antitoxin system RelE/ParE family toxinToxin
EL341_RS062751437364..1438788-1425WP_126467368.1tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB-
EL341_RS062801438947..1440137+1191WP_126467370.12-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-95)

Antitoxin

Antitoxin ParD

(4-74)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 12054.88 Da        Isoelectric Point: 9.2358

>T288022 WP_126467366.1 NZ_LR134531:1436965-1437270 [Pragia fontium]
MLKSKEVRLTPKAISDLENIYEYSHREFGQIKAERYIRRIDAALNKLADFPRSGIHYFHLAEDLMGYKVESHIVFYRVQH
DVISVLRVLHKSMDYAEHIHR

Download         Length: 306 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9748.01 Da        Isoelectric Point: 4.4764

>AT288022 WP_047780617.1 NZ_LR134531:1436721-1436978 [Pragia fontium]
MARTMTITPGEELRQFVEGLVEAGIYQTNSEVVREGLRMLQEKYAASQLTLLRQLIDEGEQSGEAVTWNSQDFIRRMNQL
KDAEK

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A0G3CPL6

References