Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prpT-prpA/ParE-CC2985
Location 1436721..1437270 Replicon chromosome
Accession NZ_LR134531
Organism Pragia fontium strain NCTC12284

Toxin (Protein)


Gene name PrpT Uniprot ID -
Locus tag EL341_RS06270 Protein ID WP_126467366.1
Coordinates 1436965..1437270 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name PrpA Uniprot ID A0A0G3CPL6
Locus tag EL341_RS06265 Protein ID WP_047780617.1
Coordinates 1436721..1436978 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL341_RS06250 1432409..1433944 - 1536 WP_126467362.1 apolipoprotein N-acyltransferase -
EL341_RS17655 1433952..1434830 - 879 WP_047780614.1 CNNM family magnesium/cobalt transport protein CorC -
EL341_RS17660 1434849..1435322 - 474 WP_047780615.1 rRNA maturation RNase YbeY -
EL341_RS06260 1435335..1436390 - 1056 WP_126467364.1 PhoH family protein -
EL341_RS06265 1436721..1436978 + 258 WP_047780617.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
EL341_RS06270 1436965..1437270 + 306 WP_126467366.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL341_RS06275 1437364..1438788 - 1425 WP_126467368.1 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB -
EL341_RS06280 1438947..1440137 + 1191 WP_126467370.1 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-95)

Antitoxin

Antitoxin ParD

(4-74)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 12054.88 Da        Isoelectric Point: 9.2358

>T288022 WP_126467366.1 NZ_LR134531:1436965-1437270 [Pragia fontium]
MLKSKEVRLTPKAISDLENIYEYSHREFGQIKAERYIRRIDAALNKLADFPRSGIHYFHLAEDLMGYKVESHIVFYRVQH
DVISVLRVLHKSMDYAEHIHR

Download         Length: 306 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9748.01 Da        Isoelectric Point: 4.4764

>AT288022 WP_047780617.1 NZ_LR134531:1436721-1436978 [Pragia fontium]
MARTMTITPGEELRQFVEGLVEAGIYQTNSEVVREGLRMLQEKYAASQLTLLRQLIDEGEQSGEAVTWNSQDFIRRMNQL
KDAEK

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0G3CPL6

References