Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-DUF971
Location 1852061..1852631 Replicon chromosome
Accession NZ_LR134529
Organism Bartonella vinsonii strain NCTC12905

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag EL291_RS08370 Protein ID WP_126603892.1
Coordinates 1852323..1852631 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag EL291_RS08365 Protein ID WP_126603891.1
Coordinates 1852061..1852342 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL291_RS08335 1847250..1847456 - 207 WP_004865664.1 hypothetical protein -
EL291_RS08340 1847676..1848842 - 1167 WP_126603886.1 site-specific integrase -
EL291_RS08345 1849118..1850011 + 894 WP_126603887.1 hypothetical protein -
EL291_RS08350 1850103..1851230 + 1128 WP_126603888.1 N4-gp56 family major capsid protein -
EL291_RS08355 1851251..1851631 + 381 WP_126603889.1 hypothetical protein -
EL291_RS08360 1851643..1852023 + 381 WP_126603890.1 hypothetical protein -
EL291_RS08365 1852061..1852342 - 282 WP_126603891.1 putative addiction module antidote protein Antitoxin
EL291_RS08370 1852323..1852631 - 309 WP_126603892.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL291_RS08375 1852695..1853399 + 705 WP_126604068.1 hypothetical protein -
EL291_RS08380 1853401..1854858 + 1458 WP_126603893.1 hypothetical protein -
EL291_RS08385 1854858..1855283 + 426 WP_126603894.1 hypothetical protein -
EL291_RS08390 1855285..1856124 + 840 WP_126603895.1 hypothetical protein -
EL291_RS08395 1856148..1857479 + 1332 WP_126603896.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1847676..1883687 36011


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-91)

Antitoxin

Uncharacterized protein HI1420

(3-89)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11792.79 Da        Isoelectric Point: 9.8192

>T288019 WP_126603892.1 NZ_LR134529:c1852631-1852323 [Bartonella vinsonii]
MVVIHKTIEFDTWLKKLKDKSAKAIILQRVVRLKQGLLGDVKFFHGIGELRIHYGAGYRVYFTQKGSEFILLLCGGDKST
QKKDIEQALKLKEEYSDENYTI

Download         Length: 309 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10174.48 Da        Isoelectric Point: 5.0931

>AT288019 WP_126603891.1 NZ_LR134529:c1852342-1852061 [Bartonella vinsonii]
MKTTPFKPEEYLETTEEQQIFLNEAFKTGDAAHIADALGIVARAQNMSTLAKETNRERSGLYRSLSKTGDPKLSTLVAVL
SALNLQLSVESTS

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References