288012

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) FicTA/Fic(toxin)
Location 1616991..1617759 Replicon chromosome
Accession NZ_LR134527
Organism Bartonella elizabethae strain NCTC12898

Toxin (Protein)


Gene name VbhT Uniprot ID J1K919
Locus tag EL285_RS07100 Protein ID WP_005774621.1
Coordinates 1616991..1617584 (-) Length 198 a.a.

Antitoxin (Protein)


Gene name VbhA Uniprot ID J0RDB0
Locus tag EL285_RS07105 Protein ID WP_005775231.1
Coordinates 1617571..1617759 (-) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL285_RS07060 1612038..1612889 + 852 WP_005775234.1 P-type conjugative transfer protein VirB9 -
EL285_RS07065 1612937..1614121 + 1185 WP_005775233.1 type IV secretion system protein VirB10 -
EL285_RS07070 1614187..1615239 + 1053 WP_005774626.1 P-type DNA transfer ATPase VirB11 -
EL285_RS07075 1615390..1615773 + 384 WP_005775232.1 EexN family lipoprotein -
EL285_RS07080 1615776..1616075 + 300 WP_026501012.1 EexN family lipoprotein -
EL285_RS07090 1616399..1616683 + 285 WP_005774622.1 EexN family lipoprotein -
EL285_RS07095 1616745..1617048 + 304 Protein_1324 type IV secretion system protein -
EL285_RS07100 1616991..1617584 - 594 WP_005774621.1 Fic family protein Toxin
EL285_RS07105 1617571..1617759 - 189 WP_005775231.1 antitoxin VbhA family protein Antitoxin
EL285_RS07110 1617959..1618204 - 246 WP_005775230.1 HigA family addiction module antidote protein -
EL285_RS07115 1618459..1618833 - 375 WP_026501011.1 hypothetical protein -
EL285_RS07125 1619982..1620338 + 357 WP_005775227.1 helix-turn-helix domain-containing protein -
EL285_RS07130 1620789..1622144 - 1356 WP_005774616.1 phosphoglucosamine mutase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(55-150)

Antitoxin

Antitoxin VbhA-like

(4-57)


Sequences

Toxin        


Download         Length: 198 a.a.        Molecular weight: 22758.72 Da        Isoelectric Point: 6.7611

>T288012 WP_005774621.1 NZ_LR134527:c1617584-1616991 [Bartonella elizabethae]
VETYKGSGDPYTDPKTGVMYNRFEIQDKTVLERVESTFAYVRSFELMRAARGGKFDLNHMKDIHKKLFGDVYEWAGEIRS
IDITKGGCLFAYHHQIESYTPKITQQLAKEQYLRGLDADEFSQRAGYYMGEINALHPFREGNGRTQREFIGQLAREAGYH
INWKGITRQEMIEASIEALYGTSELLSELIRKNLNLL

Download         Length: 594 bp

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 7150.19 Da        Isoelectric Point: 4.3700

>AT288012 WP_005775231.1 NZ_LR134527:c1617759-1617571 [Bartonella elizabethae]
MLSEEEIKQRRFAAENALVSQRLEGLEPDPKVVEQMERVIIGELETSDIIKDLLERVKRGDV

Download         Length: 189 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB J1K919

Antitoxin

Source ID Structure
AlphaFold DB J0RDB0

References