Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-DUF971
Location 988118..988691 Replicon chromosome
Accession NZ_LR134527
Organism Bartonella elizabethae strain NCTC12898

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag EL285_RS04315 Protein ID WP_026500960.1
Coordinates 988118..988426 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID J1A1Y8
Locus tag EL285_RS04320 Protein ID WP_005775091.1
Coordinates 988407..988691 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL285_RS09040 983288..984580 - 1293 WP_195890864.1 hypothetical protein -
EL285_RS04295 984612..985457 - 846 WP_005775097.1 hypothetical protein -
EL285_RS04300 985459..985884 - 426 WP_005775096.1 hypothetical protein -
EL285_RS04305 985884..987344 - 1461 WP_005775095.1 hypothetical protein -
EL285_RS04310 987346..988053 - 708 WP_005775094.1 hypothetical protein -
EL285_RS04315 988118..988426 + 309 WP_026500960.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL285_RS04320 988407..988691 + 285 WP_005775091.1 putative addiction module antidote protein Antitoxin
EL285_RS04325 988721..989101 - 381 WP_005775090.1 hypothetical protein -
EL285_RS04330 989113..989493 - 381 WP_005775089.1 hypothetical protein -
EL285_RS04335 989515..990642 - 1128 WP_005775088.1 N4-gp56 family major capsid protein -
EL285_RS04340 990731..991618 - 888 WP_005775087.1 hypothetical protein -
EL285_RS04345 991632..993650 - 2019 WP_026500959.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 971589..1023955 52366


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-91)

Antitoxin

Uncharacterized protein HI1420

(14-91)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11814.73 Da        Isoelectric Point: 8.8711

>T288011 WP_026500960.1 NZ_LR134527:988118-988426 [Bartonella elizabethae]
MMLIHKTIEFDTWLEKLKDKTAKAIILQRVVRLKQGLLGDVKFFHGIGELRIHYGAGYRVYFTQKGSDFILLLCGGDKST
QQRDIEQALKLKEEYSDENNPI

Download         Length: 309 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10230.74 Da        Isoelectric Point: 8.0048

>AT288011 WP_005775091.1 NZ_LR134527:988407-988691 [Bartonella elizabethae]
MKITPFEPEKYLKDIESQQIFLNEALKTGDAAHIADAIGIVARAQNMSALAKETNRERSGLYRSLSKTGDPKLSTLVAVL
SALNLQLSVQPCNS

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB J1A1Y8

References