Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 660965..661445 Replicon chromosome
Accession NZ_LR134527
Organism Bartonella elizabethae strain NCTC12898

Toxin (Protein)


Gene name pasB Uniprot ID J1A2R4
Locus tag EL285_RS02825 Protein ID WP_005773373.1
Coordinates 661176..661445 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID J0RIR3
Locus tag EL285_RS02820 Protein ID WP_005773372.1
Coordinates 660965..661192 (+) Length 76 a.a.

Genomic Context


EL285_RS02785EL285_RS02790EL285_RS02795EL285_RS02810EL285_RS02815EL285_RS02820EL285_RS02825EL285_RS02830EL285_RS02835EL285_RS02800EL285_RS02805EL285_RS02840EL285_RS02845
Location: 656531..656992 (462 bp)
Type: Others
Protein ID: WP_078674257.1
Location: 657263..657781 (519 bp)
Type: Others
Protein ID: WP_005773365.1
Location: 657862..658563 (702 bp)
Type: Others
Protein ID: WP_005773367.1
Location: 659877..660314 (438 bp)
Type: Others
Protein ID: WP_005773370.1
Location: 660330..660866 (537 bp)
Type: Others
Protein ID: WP_005773371.1
Location: 660965..661192 (228 bp)
Type: Antitoxin
Protein ID: WP_005773372.1
Location: 661176..661445 (270 bp)
Type: Toxin
Protein ID: WP_005773373.1
Location: 661633..661968 (336 bp)
Type: Others
Protein ID: WP_005773374.1
Location: 661970..663142 (1173 bp)
Type: Others
Protein ID: WP_005773375.1
Location: 658633..658950 (318 bp)
Type: Others
Protein ID: WP_005773368.1
Location: 658940..659218 (279 bp)
Type: Others
Protein ID: WP_005773369.1
Location: 664607..665386 (780 bp)
Type: Others
Protein ID: WP_005773376.1
Location: 665482..666102 (621 bp)
Type: Others
Protein ID: WP_005773377.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EL285_RS02785656531..656992+462WP_078674257.1hypothetical protein-
EL285_RS02790657263..657781+519WP_005773365.1Rha family transcriptional regulator-
EL285_RS02795657862..658563+702WP_005773367.1hypothetical protein-
EL285_RS02800658633..658950-318WP_005773368.1type II toxin-antitoxin system HicB family antitoxin-
EL285_RS02805658940..659218-279WP_005773369.1hypothetical protein-
EL285_RS02810659877..660314+438WP_005773370.1single-stranded DNA-binding protein-
EL285_RS02815660330..660866+537WP_005773371.1hypothetical protein-
EL285_RS02820660965..661192+228WP_005773372.1ribbon-helix-helix protein, CopG familyAntitoxin
EL285_RS02825661176..661445+270WP_005773373.1type II toxin-antitoxin system RelE/ParE family toxinToxin
EL285_RS02830661633..661968+336WP_005773374.1hypothetical protein-
EL285_RS02835661970..663142+1173WP_005773375.1phage terminase large subunit-
EL285_RS02840664607..665386-780WP_005773376.1hypothetical protein-
EL285_RS02845665482..666102-621WP_005773377.1hypothetical protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--636268..68388447616


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 90 a.a.        Molecular weight: 10544.46 Da        Isoelectric Point: 10.2297

>T288009 WP_005773373.1 NZ_LR134527:661176-661445 [Bartonella elizabethae]
MVWTIRYEKKALSFLKKCDKKEARRIVDFLDQQIASLEDVRTIGKPLRGQLSGLWRYRVGDYRILCELYDKELVVLVLAV
GHRKNIYKS

Download         Length: 270 bp


Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8784.86 Da        Isoelectric Point: 4.8898

>AT288009 WP_005773372.1 NZ_LR134527:660965-661192 [Bartonella elizabethae]
MTISIRLPSELETRLNNLAAKTGRTKSFYLREIIERGIEEAEDYYLASQVRERIRRGEATFYSSEEVRKELGLDD

Download         Length: 228 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBJ1A2R4


Antitoxin

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Source
ID
Structure
AlphaFold DBJ0RIR3

References