Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 1366984..1367524 Replicon chromosome
Accession NZ_LR134524
Organism Peptoniphilus harei strain NCTC13077

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EL281_RS06535 Protein ID WP_126439609.1
Coordinates 1366984..1367262 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EL281_RS06540 Protein ID WP_126439610.1
Coordinates 1367252..1367524 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL281_RS06505 1362901..1364529 - 1629 WP_126439607.1 AAA family ATPase -
EL281_RS06510 1364552..1364758 - 207 WP_006701958.1 helix-turn-helix transcriptional regulator -
EL281_RS06520 1365701..1365952 + 252 Protein_1248 plasmid mobilization relaxosome protein MobC -
EL281_RS06525 1366200..1366388 - 189 Protein_1249 tail tape measure protein -
EL281_RS06530 1366473..1366760 - 288 WP_126439608.1 hypothetical protein -
EL281_RS08245 1366778..1366948 - 171 WP_164753367.1 hypothetical protein -
EL281_RS06535 1366984..1367262 - 279 WP_126439609.1 type II toxin-antitoxin system YafQ family toxin Toxin
EL281_RS06540 1367252..1367524 - 273 WP_126439610.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
EL281_RS06545 1367614..1367829 - 216 WP_126439611.1 helix-turn-helix transcriptional regulator -
EL281_RS06550 1367832..1368353 - 522 WP_126439612.1 DUF2975 domain-containing protein -
EL281_RS06555 1368380..1368847 - 468 WP_126439613.1 hypothetical protein -
EL281_RS08250 1368944..1369108 - 165 WP_164753368.1 hypothetical protein -
EL281_RS06560 1369336..1369773 + 438 WP_126439614.1 hypothetical protein -
EL281_RS06565 1370307..1371617 + 1311 WP_126439615.1 aspartate kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1334264..1374971 40707


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-88)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10790.57 Da        Isoelectric Point: 9.8474

>T288005 WP_126439609.1 NZ_LR134524:c1367262-1366984 [Peptoniphilus harei]
MKYKIKFTSRFKKDLKQAKKQGKDIEKLFDVIEKIAKDEALDEKYRDHSLAGNYKGTRECHIEPNFLLIYEKIEGVLILS
LVRTGSHSDLFK

Download         Length: 279 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10123.53 Da        Isoelectric Point: 4.4944

>AT288005 WP_126439610.1 NZ_LR134524:c1367524-1367252 [Peptoniphilus harei]
MATTNLNIRTEKEIKEAAEKIYSSLGLNMTTAINMFLRASIRESGIPFELKLNVPSDETIKAIEEGRMIANDNNISSYDN
MDDLRKALEV

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References