Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH
Location 111449..111936 Replicon chromosome
Accession NZ_LR134524
Organism Peptoniphilus harei strain NCTC13077

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EL281_RS00550 Protein ID WP_126438786.1
Coordinates 111670..111936 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EL281_RS00545 Protein ID WP_040551230.1
Coordinates 111449..111673 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL281_RS00530 107377..108636 + 1260 WP_126438783.1 erythromycin esterase family protein -
EL281_RS00535 108661..109407 + 747 WP_126438784.1 ABC transporter ATP-binding protein -
EL281_RS00540 109412..111391 + 1980 WP_126438785.1 FtsX-like permease family protein -
EL281_RS00545 111449..111673 + 225 WP_040551230.1 toxin-antitoxin system protein Antitoxin
EL281_RS00550 111670..111936 + 267 WP_126438786.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL281_RS00555 111994..112776 + 783 WP_126438787.1 ADP-ribosylglycohydrolase family protein -
EL281_RS00560 112901..113458 - 558 WP_126438788.1 chromate transporter -
EL281_RS00565 113451..114011 - 561 WP_126438789.1 chromate transporter -
EL281_RS00570 114090..114854 + 765 WP_112889574.1 pyrroline-5-carboxylate reductase -
EL281_RS00575 114864..115430 + 567 WP_070699995.1 DJ-1/PfpI family protein -
EL281_RS00580 115624..116772 + 1149 WP_112889573.1 cation diffusion facilitator family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

Protein of unknown function DUF6290

(1-72)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10499.21 Da        Isoelectric Point: 10.6770

>T288004 WP_126438786.1 NZ_LR134524:111670-111936 [Peptoniphilus harei]
MTYQVRTTKKFDKSFKKLDRQSQKLIKNWIEGNLMDCPDPRFSGKPLTGNFKGVWRYRIGSYRLLTKIDDDKLIIFAIDV
GHRRNIYN

Download         Length: 267 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8715.88 Da        Isoelectric Point: 4.1049

>AT288004 WP_040551230.1 NZ_LR134524:111449-111673 [Peptoniphilus harei]
MKTVSVRLNAEEERAFTAYADLMGEPLSTLFKRLMEEKLEDEFDMKVAEDFLEREARGEVETRPIEDLFKELDL

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References