Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 1063391..1064012 Replicon chromosome
Accession NZ_LR134519
Organism Helicobacter pylori strain NCTC12823

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EL264_RS05135 Protein ID WP_126474498.1
Coordinates 1063391..1063657 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EL264_RS05140 Protein ID WP_126474499.1
Coordinates 1063638..1064012 (-) Length 125 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL264_RS05100 (NCTC12823_01016) 1059208..1059975 - 768 WP_000242349.1 ABC transporter ATP-binding protein -
EL264_RS05105 (NCTC12823_01017) 1059975..1060955 - 981 WP_000921458.1 iron chelate uptake ABC transporter family permease subunit -
EL264_RS05110 (NCTC12823_01018) 1060948..1061811 - 864 WP_126474495.1 SDR family oxidoreductase -
EL264_RS05115 (NCTC12823_01019) 1061951..1062475 + 525 WP_001135603.1 acyl-CoA thioesterase -
EL264_RS05125 1062672..1062957 - 286 Protein_974 endoribonuclease VapD -
EL264_RS05130 (NCTC12823_01020) 1062938..1063330 - 393 WP_126474497.1 hypothetical protein -
EL264_RS05135 (NCTC12823_01021) 1063391..1063657 - 267 WP_126474498.1 type II toxin-antitoxin system YafQ family toxin Toxin
EL264_RS05140 (NCTC12823_01022) 1063638..1064012 - 375 WP_126474499.1 hypothetical protein Antitoxin
EL264_RS05145 (NCTC12823_01023) 1064568..1066802 - 2235 WP_126474500.1 Hop family adhesin BabA -
EL264_RS05160 1067370..1068003 + 634 Protein_979 helicase DnaB modulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10293.31 Da        Isoelectric Point: 10.3034

>T287999 WP_126474498.1 NZ_LR134519:c1063657-1063391 [Helicobacter pylori]
VLKLNLKKSFQKDFDKLLLNGFDDSVLNKVILTLRKKEPLPPPFKDHALKGKWKPFRECHIKPDVLLVYLVKDNELILLR
LGSHSELF

Download         Length: 267 bp

Antitoxin


Download         Length: 125 a.a.        Molecular weight: 14640.66 Da        Isoelectric Point: 8.9992

>AT287999 WP_126474499.1 NZ_LR134519:c1064012-1063638 [Helicobacter pylori]
MPNTTNKDYTKYSEKQLFNLIHQLERKIKKMQNDRVSFKEKMAKELEKRDQNFKDKIDALKELLQKISQAFDDKRDCCLG
HEIPNLQTQQAIRDALNKETDLIVEDFSSYSDERKKALGVKTQS

Download         Length: 375 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References