Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 1227971..1228445 Replicon chromosome
Accession NZ_LR134517
Organism Helicobacter pylori strain NCTC13345

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EL256_RS05925 Protein ID WP_126443252.1
Coordinates 1228140..1228445 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EL256_RS05920 Protein ID WP_126443250.1
Coordinates 1227971..1228159 (+) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL256_RS05905 1223150..1223905 + 756 WP_121089405.1 HugZ family heme oxygenase -
EL256_RS05910 1224194..1226248 + 2055 WP_126443246.1 outer membrane beta-barrel protein -
EL256_RS05915 1227795..1227974 + 180 WP_126443248.1 hypothetical protein -
EL256_RS05920 1227971..1228159 + 189 WP_126443250.1 hypothetical protein Antitoxin
EL256_RS05925 1228140..1228445 + 306 WP_126443252.1 type II toxin-antitoxin system YafQ family toxin Toxin
EL256_RS05930 1228564..1229906 - 1343 Protein_1116 IS200/IS605 family accessory protein TnpB-related protein -
EL256_RS05935 1229903..1230229 - 327 Protein_1117 IS607 family transposase -
EL256_RS05940 1230554..1231699 + 1146 WP_001263615.1 YbfB/YjiJ family MFS transporter -
EL256_RS05945 1231705..1232670 - 966 WP_126443254.1 GTP-binding protein -
EL256_RS05950 1232670..1233047 - 378 WP_126443256.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11699.02 Da        Isoelectric Point: 9.9967

>T287997 WP_126443252.1 NZ_LR134517:1228140-1228445 [Helicobacter pylori]
VLKLNLKKSFQKDFDKLLLNGFDDSVLKEVILRKKEPLPPPFKDHALKGVWKPFRECHIKADVLLVYLVKDDELILLRLG
SHSELFYKLPITLKKNATIAC

Download         Length: 306 bp

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 7123.85 Da        Isoelectric Point: 4.5338

>AT287997 WP_126443250.1 NZ_LR134517:1227971-1228159 [Helicobacter pylori]
MNKILQEINKRANDCCFGHETPNIETQQAMREADNKETDLFVEDFSSYSNERKKALGVEAQS

Download         Length: 189 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References