287995

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 20927..22094 Replicon chromosome
Accession NZ_LR134517
Organism Helicobacter pylori strain NCTC13345

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag EL256_RS00085 Protein ID WP_126442262.1
Coordinates 21354..22094 (+) Length 247 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag EL256_RS00080 Protein ID WP_126442261.1
Coordinates 20927..21364 (+) Length 146 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL256_RS00075 19075..20703 + 1629 WP_126442260.1 RNA-directed DNA polymerase -
EL256_RS00080 20927..21364 + 438 WP_126442261.1 SocA family protein Antitoxin
EL256_RS00085 21354..22094 + 741 WP_126442262.1 hypothetical protein Toxin
EL256_RS00090 22361..23548 - 1188 WP_126442263.1 transcription termination/antitermination protein NusA -
EL256_RS00095 23644..24816 - 1173 WP_126442264.1 L-seryl-tRNA(Sec) selenium transferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(24-119)


Sequences

Toxin        


Download         Length: 247 a.a.        Molecular weight: 28733.49 Da        Isoelectric Point: 6.7158

>T287995 WP_126442262.1 NZ_LR134517:21354-22094 [Helicobacter pylori]
METKEEDKDKKLEEMIVLLCEKGDLSSQTDQIIKDLKEIYEGEYRHKYSKITTIILNSTRDKEQAFMTLAQNIRTLKEIQ
DNKEVESIKPKLEKLYDHMNLECIRLQDFDEKMSRVKDVSNKLEDDLNKNYKKLSEELNKQQTQYITILGIFASIVLTFV
GGLAFSTSVLSNIDKANAYRLVFVMAFIALFFGNILYLLFSFLSKVSLSKEKKDKQENFCKKPMFWFNLIVTILFVIGFC
GELHII

Download         Length: 741 bp

Antitoxin


Download         Length: 146 a.a.        Molecular weight: 17309.38 Da        Isoelectric Point: 6.3457

>AT287995 WP_126442261.1 NZ_LR134517:20927-21364 [Helicobacter pylori]
MVNTLELAQYILKHSNKELSNLELQKTLYFTELDYIKKFDKHLVSDDFEAWKYGPVAREVYYEYRNYGANSIDKPKEETL
SQNLRKDELETINHSIEKCNEKSYWDLVKESHKENGAWHKSFKEDRKEIISKDLIKQEAKQTNGN

Download         Length: 438 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References