Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 260007..260526 Replicon chromosome
Accession NZ_LR134516
Organism Neisseria animaloris strain NCTC12227

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EL276_RS01080 Protein ID WP_085389274.1
Coordinates 260007..260273 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag EL276_RS01085 Protein ID WP_126303796.1
Coordinates 260260..260526 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL276_RS01060 255701..256123 - 423 WP_126303790.1 hypothetical protein -
EL276_RS01065 256346..256987 - 642 WP_085356016.1 orotate phosphoribosyltransferase -
EL276_RS01070 257235..259748 + 2514 WP_126303792.1 TonB-dependent receptor -
EL276_RS01080 260007..260273 - 267 WP_085389274.1 type II toxin-antitoxin system YafQ family toxin Toxin
EL276_RS01085 260260..260526 - 267 WP_126303796.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
EL276_RS01090 260695..261471 + 777 WP_126305194.1 exodeoxyribonuclease III -
EL276_RS01095 261540..261737 + 198 WP_085389276.1 DUF1737 domain-containing protein -
EL276_RS01100 261753..262286 + 534 WP_107878645.1 alpha/beta hydrolase -
EL276_RS01105 262372..264042 - 1671 WP_126303798.1 FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC -
EL276_RS01110 264227..264967 + 741 WP_126303800.1 orotidine-5'-phosphate decarboxylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-84)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10155.68 Da        Isoelectric Point: 7.3242

>T287992 WP_085389274.1 NZ_LR134516:c260273-260007 [Neisseria animaloris]
MKAIEFSNAFKRDFKKYPALALSTRWIEALYCICSEQTLPPKFCDHALTGNWHGFRDCHIEPDLVLIYRHTENTVELARI
GTHSALFG

Download         Length: 267 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9610.83 Da        Isoelectric Point: 4.5183

>AT287992 WP_126303796.1 NZ_LR134516:c260526-260260 [Neisseria animaloris]
MAANALVSVRINEDVKNQASAVLAGAGLTISDVIRMTLTKIATEQRFSFDYQPNVETARVLTAMQNGTETLHRADSVEAL
MERLNESD

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References