Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-virA/YafQ(toxin)
Location 1372091..1372647 Replicon chromosome
Accession NZ_LR134509
Organism Helicobacter pullorum strain NCTC13154

Toxin (Protein)


Gene name relE Uniprot ID A0A0N1ECB2
Locus tag EL247_RS06685 Protein ID WP_054197523.1
Coordinates 1372372..1372647 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name virA Uniprot ID -
Locus tag EL247_RS06680 Protein ID WP_104745810.1
Coordinates 1372091..1372372 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL247_RS06655 1367349..1368794 + 1446 WP_104745809.1 NAD(P)H-hydrate dehydratase -
EL247_RS06660 1368824..1369606 + 783 WP_060663212.1 thiazole synthase -
EL247_RS06665 1369616..1370227 + 612 WP_054197525.1 recombination protein RecO -
EL247_RS06670 1370293..1370709 + 417 WP_104745826.1 pyridoxamine 5'-phosphate oxidase family protein -
EL247_RS06675 1370847..1371896 + 1050 WP_054195611.1 tRNA 2-thiouridine(34) synthase MnmA -
EL247_RS06680 1372091..1372372 + 282 WP_104745810.1 hypothetical protein Antitoxin
EL247_RS06685 1372372..1372647 + 276 WP_054197523.1 type II toxin-antitoxin system YafQ family toxin Toxin
EL247_RS06690 1372891..1373715 + 825 WP_065826375.1 universal stress protein -
EL247_RS06695 1373726..1375009 + 1284 WP_054197521.1 ComEC/Rec2 family competence protein -
EL247_RS06700 1375158..1375700 + 543 WP_005022703.1 DUF502 domain-containing protein -
EL247_RS06705 1375700..1376554 + 855 WP_005022702.1 4-hydroxybenzoate polyprenyltransferase -
EL247_RS06710 1376571..1377119 + 549 WP_005022701.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10928.59 Da        Isoelectric Point: 8.8068

>T287983 WP_054197523.1 NZ_LR134509:1372372-1372647 [Helicobacter pullorum]
MRKIDIKNTFKKDYRQVLKQGWSENAIDEVIKQLANDDILNPQLKPHPLGGDYKNYMECHIFSDLIIIYQRDKEILSLYR
IGRHQDLFKSY

Download         Length: 276 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10913.42 Da        Isoelectric Point: 10.2896

>AT287983 WP_104745810.1 NZ_LR134509:1372091-1372372 [Helicobacter pullorum]
MFDYAKYENATQKEIIHALNLTQRKSEKLNQQLKENREIFKFLQKKLKESFSSKKNKKNNIPNSKTINVLNNNTSIGVFN
DFDEAKKALMSDE

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0N1ECB2

Antitoxin

Source ID Structure

References