Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1645172..1645713 Replicon chromosome
Accession NZ_LR134503
Organism Kaistella jeonii strain NCTC13459

Toxin (Protein)


Gene name parE Uniprot ID A0A0C1FD02
Locus tag EL270_RS07480 Protein ID WP_039348934.1
Coordinates 1645417..1645713 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A0C1F989
Locus tag EL270_RS07475 Protein ID WP_039348931.1
Coordinates 1645172..1645420 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL270_RS07445 1640656..1640937 + 282 WP_039348914.1 1,2-phenylacetyl-CoA epoxidase subunit B -
EL270_RS07450 1641029..1641778 + 750 WP_039348917.1 phenylacetate-CoA oxygenase subunit PaaC -
EL270_RS07455 1641907..1642380 + 474 WP_039348920.1 phenylacetate-CoA oxygenase subunit PaaJ -
EL270_RS07460 1642547..1643344 + 798 WP_039348922.1 enoyl-CoA hydratase/isomerase family protein -
EL270_RS07465 1643428..1644564 + 1137 WP_039348924.1 3-hydroxybutyryl-CoA dehydrogenase -
EL270_RS07470 1644636..1645049 + 414 WP_039348928.1 hotdog fold thioesterase -
EL270_RS07475 1645172..1645420 + 249 WP_039348931.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
EL270_RS07480 1645417..1645713 + 297 WP_039348934.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL270_RS07485 1646035..1646547 + 513 WP_039348938.1 sigma-70 family RNA polymerase sigma factor -
EL270_RS07490 1646559..1647224 + 666 WP_039348941.1 hypothetical protein -
EL270_RS15150 1647236..1648501 + 1266 WP_052257369.1 DUF4252 domain-containing protein -
EL270_RS07500 1648506..1649030 + 525 WP_039348942.1 DUF4252 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Antitoxin ParD

(1-76)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 12139.65 Da        Isoelectric Point: 5.6926

>T287981 WP_039348934.1 NZ_LR134503:1645417-1645713 [Kaistella jeonii]
MIFEISEKANEDLENIWLYTYENWSQEQADRYYNLILNEIEYITENFESGKSFEHIRKGYRSTKVKSHLIFYRKSKRDTI
EIIRILHQRMDIENRLNE

Download         Length: 297 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9410.77 Da        Isoelectric Point: 9.6573

>AT287981 WP_039348931.1 NZ_LR134503:1645172-1645420 [Kaistella jeonii]
MGKNTSILLGDYFENFVNEKITSGKFSSVSEVIRNALRLMENEENKTKTLINELKIGEKSGIVKDFDRNENLNKIHSKHL
IK

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C1FD02

Antitoxin

Source ID Structure
AlphaFold DB A0A0C1F989

References