287974

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4315652..4316321 Replicon chromosome
Accession NZ_LR134494
Organism Serratia quinivorans strain NCTC13188

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag EL336_RS20380 Protein ID WP_112363195.1
Coordinates 4315652..4316074 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A2X2H1C0
Locus tag EL336_RS20385 Protein ID WP_012146600.1
Coordinates 4316055..4316321 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL336_RS20360 4311540..4312058 + 519 WP_017893855.1 flavodoxin FldB -
EL336_RS20365 4312095..4313459 - 1365 WP_112363197.1 cell envelope integrity protein CreD -
EL336_RS20370 4313542..4314960 - 1419 WP_112363196.1 two-component system sensor histidine kinase CreC -
EL336_RS20375 4314957..4315652 - 696 WP_012146598.1 two-component system response regulator CreB -
EL336_RS20380 4315652..4316074 - 423 WP_112363195.1 protein YgfX Toxin
EL336_RS20385 4316055..4316321 - 267 WP_012146600.1 FAD assembly factor SdhE Antitoxin
EL336_RS20390 4316645..4317637 + 993 WP_112363194.1 tRNA-modifying protein YgfZ -
EL336_RS20395 4317728..4318402 - 675 WP_012146602.1 hemolysin III family protein -
EL336_RS20400 4318586..4319194 + 609 WP_012146603.1 HD domain-containing protein -
EL336_RS20405 4319245..4320569 - 1325 Protein_3956 MHS family MFS transporter -
EL336_RS20410 4320566..4321219 - 654 WP_112363192.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16524.42 Da        Isoelectric Point: 10.7372

>T287974 WP_112363195.1 NZ_LR134494:c4316074-4315652 [Serratia quinivorans]
VAQWRCDVRISWRTQLFSLLTHGVLILLILISPWPEGYGPIWLVLLTLVVFECIRSQKRIASRQGELRLLENQRLGWHGQ
EWQLLKQPWMPRYGILLTLQPVGGKKRRRLWLASDSMAKADWRQLRQRLLYPPASDDEEA

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10457.96 Da        Isoelectric Point: 4.7921

>AT287974 WP_012146600.1 NZ_LR134494:c4316321-4316055 [Serratia quinivorans]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDLLNDTDKALFIRLLESDDPDLFNWLMNHGAPQDSELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2X2H1C0

References