Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1744623..1745148 Replicon chromosome
Accession NZ_LR134494
Organism Serratia quinivorans strain NCTC13188

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EL336_RS08365 Protein ID WP_112363519.1
Coordinates 1744623..1744907 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2X2H0U4
Locus tag EL336_RS08370 Protein ID WP_012006084.1
Coordinates 1744897..1745148 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL336_RS08340 1739788..1740921 + 1134 WP_012006079.1 putrescine ABC transporter ATP-binding subunit PotG -
EL336_RS08345 1740953..1741912 + 960 WP_026142288.1 putrescine ABC transporter permease PotH -
EL336_RS08350 1741909..1742754 + 846 WP_012006081.1 putrescine ABC transporter permease PotI -
EL336_RS08355 1742951..1743430 + 480 WP_041418514.1 DUF2593 family protein -
EL336_RS08360 1743499..1744626 + 1128 WP_112363518.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
EL336_RS08365 1744623..1744907 - 285 WP_112363519.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL336_RS08370 1744897..1745148 - 252 WP_012006084.1 prevent-host-death protein Antitoxin
EL336_RS08375 1745258..1745992 - 735 WP_112363520.1 arginine ABC transporter substrate-binding protein -
EL336_RS08380 1746201..1746869 - 669 WP_012006086.1 arginine ABC transporter permease ArtM -
EL336_RS08385 1746869..1747585 - 717 WP_112363521.1 arginine ABC transporter permease ArtQ -
EL336_RS08390 1747594..1748325 - 732 WP_012006088.1 arginine ABC transporter substrate-binding protein -
EL336_RS08395 1748359..1749087 - 729 WP_012006089.1 arginine ABC transporter ATP-binding protein ArtP -
EL336_RS08400 1749349..1749897 - 549 WP_012006090.1 lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10835.87 Da        Isoelectric Point: 10.3031

>T287966 WP_112363519.1 NZ_LR134494:c1744907-1744623 [Serratia quinivorans]
MTYNLEFEEHALKEFKKLAPVIREQFKKKLVAVLENPLVPANKLSGLPDCYKIKLRASGYRLVYRVIGEEIVVLVLSIGK
RERSEAYTSAKKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9041.41 Da        Isoelectric Point: 5.0188

>AT287966 WP_012006084.1 NZ_LR134494:c1745148-1744897 [Serratia quinivorans]
MIVQPILADSAVSISDFKKSPNAALKEAHGQPVAVLTNGKISGYYVSPETWQAIAECLEDIELAEIVRSRMSGKRIKVNL
DDL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2X2H0U4

References