Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3624141..3624814 Replicon chromosome
Accession NZ_LR134493
Organism Serratia rubidaea strain NCTC10036

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EL320_RS17285 Protein ID WP_126532065.1
Coordinates 3624374..3624814 (+) Length 147 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EL320_RS17280 Protein ID WP_126532064.1
Coordinates 3624141..3624377 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL320_RS17255 3619325..3620929 + 1605 WP_126532060.1 Tar ligand binding domain-containing protein -
EL320_RS17260 3620958..3621818 + 861 WP_126532061.1 protein-glutamate O-methyltransferase CheR -
EL320_RS17265 3621818..3622867 + 1050 WP_126532062.1 chemotaxis response regulator protein-glutamate methylesterase -
EL320_RS17270 3622965..3623354 + 390 WP_126532063.1 chemotaxis response regulator CheY -
EL320_RS17275 3623367..3624011 + 645 WP_015672840.1 protein phosphatase CheZ -
EL320_RS17280 3624141..3624377 + 237 WP_126532064.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
EL320_RS17285 3624374..3624814 + 441 WP_126532065.1 type II toxin-antitoxin system VapC family toxin Toxin
EL320_RS17290 3624908..3626059 + 1152 WP_054307801.1 flagellar type III secretion system protein FlhB -
EL320_RS17295 3626052..3628133 + 2082 WP_126532066.1 flagellar biosynthesis protein FlhA -
EL320_RS17300 3628136..3628537 + 402 WP_164722856.1 flagellar protein FlhE -
EL320_RS17305 3628750..3629613 + 864 WP_126532068.1 protein deglycase HchA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

SpoVT-AbrB domain

(7-52)


Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 16257.66 Da        Isoelectric Point: 9.4598

>T287959 WP_126532065.1 NZ_LR134493:3624374-3624814 [Serratia rubidaea]
MITHMLDTNIVIYVIKRRPREVLALFNQHAGKMAISAVTYGELVHGVEKSARQVENLRVVEDFVSRLDVLPYTDKAAAHY
GNIRADLERKGSPIGVNDLHIAGHARSEGLVLVSNNLHEFARIDGLRLENWLSSPIIPPSRPSSSK

Download         Length: 441 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8906.86 Da        Isoelectric Point: 4.5702

>AT287959 WP_126532064.1 NZ_LR134493:3624141-3624377 [Serratia rubidaea]
MTIGSVFTNNRSQAVRLPAEARFPDSVSKVTVRVVGKERVLAPVENTWDSFFDQERLPGDDFLNERAAQYQAERESFE

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References