Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2635069..2635735 Replicon chromosome
Accession NZ_LR134493
Organism Serratia rubidaea strain NCTC10036

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag EL320_RS12685 Protein ID WP_126531531.1
Coordinates 2635316..2635735 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A3S4X5M7
Locus tag EL320_RS12680 Protein ID WP_054306178.1
Coordinates 2635069..2635335 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL320_RS12655 2630198..2630851 + 654 WP_126531529.1 hypothetical protein -
EL320_RS12660 2630848..2632167 + 1320 WP_015673672.1 MHS family MFS transporter -
EL320_RS12665 2632199..2632807 - 609 WP_015673671.1 HD domain-containing protein -
EL320_RS12670 2633002..2633682 + 681 WP_015673670.1 hemolysin III family protein -
EL320_RS12675 2633737..2634729 - 993 WP_126531530.1 tRNA-modifying protein YgfZ -
EL320_RS12680 2635069..2635335 + 267 WP_054306178.1 FAD assembly factor SdhE Antitoxin
EL320_RS12685 2635316..2635735 + 420 WP_126531531.1 protein YgfX Toxin
EL320_RS12690 2635767..2636285 - 519 WP_041411867.1 flavodoxin FldB -
EL320_RS12695 2636377..2637276 + 900 WP_126531532.1 site-specific tyrosine recombinase XerD -
EL320_RS12700 2637304..2638020 + 717 WP_054306176.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
EL320_RS12705 2638033..2639763 + 1731 WP_126533550.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16274.16 Da        Isoelectric Point: 11.2220

>T287958 WP_126531531.1 NZ_LR134493:2635316-2635735 [Serratia rubidaea]
VAQWRCDVRISWRTQLVSLLAHGALILLILISPWPESYDPIWLLLLTLVVFECIRSQTRIASRQGELRLLSAPQRVIWQG
KEWRLARRPWMLRGGMLLTLQASGKRKRRRLWLASDCISSAEWRQLCQRIQLAEDESEG

Download         Length: 420 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10361.79 Da        Isoelectric Point: 5.0718

>AT287958 WP_054306178.1 NZ_LR134493:2635069-2635335 [Serratia rubidaea]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDDKALFVRLLQSDDPDLFNWLMNHGAPQDAELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3S4X5M7

References