Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1917077..1917816 Replicon chromosome
Accession NZ_LR134493
Organism Serratia rubidaea strain NCTC10036

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EL320_RS09230 Protein ID WP_126531145.1
Coordinates 1917077..1917556 (-) Length 160 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EL320_RS09235 Protein ID WP_126531146.1
Coordinates 1917553..1917816 (-) Length 88 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL320_RS09215 1914190..1914663 - 474 WP_015962214.1 transcription elongation factor GreB -
EL320_RS09220 1914954..1915673 + 720 WP_004709363.1 two-component system response regulator OmpR -
EL320_RS09225 1915670..1917043 + 1374 WP_126531144.1 two-component system sensor histidine kinase EnvZ -
EL320_RS09230 1917077..1917556 - 480 WP_126531145.1 type II toxin-antitoxin system VapC family toxin Toxin
EL320_RS09235 1917553..1917816 - 264 WP_126531146.1 plasmid stabilization protein Antitoxin
EL320_RS09240 1918091..1919710 - 1620 WP_126531147.1 phosphoenolpyruvate carboxykinase (ATP) -
EL320_RS09245 1919907..1920788 - 882 WP_015962209.1 Hsp33 family molecular chaperone HslO -
EL320_RS09250 1920814..1921221 - 408 WP_126531148.1 ribosome-associated heat shock protein Hsp15 -
EL320_RS09255 1921218..1921898 - 681 WP_015962207.1 GMP/IMP nucleotidase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-124)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 160 a.a.        Molecular weight: 17842.51 Da        Isoelectric Point: 4.9342

>T287957 WP_126531145.1 NZ_LR134493:c1917556-1917077 [Serratia rubidaea]
MIILDTNVIAETLRPKPHYNVISWLNEKDNSELYLSAIVVAELFSGVACMPDGKRQQALRLRLAEAIQINFDEQILPFDA
LCAMQYAELMGRNLRQGTPMSAPDAQIAATCLQYGATLATRNTKDFLHCGIELIDPWQVPAGQRLHEDAAEYYVMSRKS

Download         Length: 480 bp


Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9864.24 Da        Isoelectric Point: 5.6211

>AT287957 WP_126531146.1 NZ_LR134493:c1917816-1917553 [Serratia rubidaea]
MATITVRNLDDEVKELLRISAAKNGHSMEEEARMILKQALMKKPARYGLGSWMHQHFAEFGGVELAIPPRDTVPPRRVTF
DDDDDQA

Download         Length: 264 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References