Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 4543821..4544409 Replicon chromosome
Accession NZ_LR134485
Organism Citrobacter youngae strain NCTC13709

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag EL296_RS22485 Protein ID WP_124021092.1
Coordinates 4543821..4544138 (+) Length 106 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag EL296_RS22490 Protein ID WP_124021093.1
Coordinates 4544131..4544409 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL296_RS22455 4539673..4540485 + 813 WP_124021087.1 shikimate 5-dehydrogenase -
EL296_RS22460 4540533..4540826 - 294 WP_124021088.1 type II toxin-antitoxin system CcdA family antitoxin -
EL296_RS22465 4540922..4541287 - 366 WP_124021089.1 hypothetical protein -
EL296_RS24180 4541419..4541592 + 174 WP_032938222.1 hypothetical protein -
EL296_RS22470 4541663..4541824 + 162 WP_005132808.1 hypothetical protein -
EL296_RS22475 4541971..4542477 - 507 WP_124021090.1 HNH endonuclease -
EL296_RS22480 4542692..4543432 - 741 WP_124021091.1 DUF2971 domain-containing protein -
EL296_RS22485 4543821..4544138 + 318 WP_124021092.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL296_RS22490 4544131..4544409 + 279 WP_124021093.1 putative addiction module antidote protein Antitoxin
EL296_RS22495 4544519..4545208 + 690 WP_032942056.1 dipeptidase PepE -
EL296_RS22500 4545270..4546901 - 1632 WP_124021094.1 Na/Pi cotransporter family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-96)

Antitoxin

Uncharacterized protein HI1420

(3-88)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11997.89 Da        Isoelectric Point: 10.1424

>T287941 WP_124021092.1 NZ_LR134485:4543821-4544138 [Citrobacter youngae]
IMEILQTTVFQRWEQNLRDRRAKTLIAARLFRLANGLAGDVKPVGEGISEMRISYGPGYRIYFKQHGCRIIILLCGGDKS
SQANNITLAKVLARSLDYQETFRHE

Download         Length: 318 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 9791.33 Da        Isoelectric Point: 6.2976

>AT287941 WP_124021093.1 NZ_LR134485:4544131-4544409 [Citrobacter youngae]
MNKLTQYDPAAALVDDEEIAVFMADALETGDATYIAKALGVVARAKGMANIAAETGLSREQLYRSFSEKGNPTLKTTLAV
MKALGIGLTLRK

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References