287939

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4287424..4287940 Replicon chromosome
Accession NZ_LR134485
Organism Citrobacter youngae strain NCTC13709

Toxin (Protein)


Gene name relE Uniprot ID A0A0D7LMW6
Locus tag EL296_RS21225 Protein ID WP_003839578.1
Coordinates 4287424..4287708 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0J1MV10
Locus tag EL296_RS21230 Protein ID WP_003839576.1
Coordinates 4287698..4287940 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL296_RS21210 4282650..4284302 + 1653 WP_124020778.1 alpha,alpha-phosphotrehalase -
EL296_RS21215 4284711..4286849 + 2139 WP_048212844.1 anaerobic ribonucleoside-triphosphate reductase -
EL296_RS21220 4286956..4287420 + 465 WP_124020779.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
EL296_RS21225 4287424..4287708 - 285 WP_003839578.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL296_RS21230 4287698..4287940 - 243 WP_003839576.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
EL296_RS21235 4288018..4289931 - 1914 WP_124020780.1 BglG family transcription antiterminator -
EL296_RS21240 4289953..4290693 - 741 WP_124020781.1 KDGP aldolase family protein -
EL296_RS21245 4290690..4291808 - 1119 WP_101743297.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
EL296_RS21250 4291792..4292925 - 1134 WP_101743296.1 amidohydrolase/deacetylase family metallohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10866.68 Da        Isoelectric Point: 10.0482

>T287939 WP_003839578.1 NZ_LR134485:c4287708-4287424 [Citrobacter youngae]
MTYELEFDPRALKEWHKLGDTVKAQFKKKLADVLLNPRIDSARLNGLPDCYKIKLKSSGYRLVYQVRDEVVTVFVVAVGK
REHSAVYLDANKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8961.34 Da        Isoelectric Point: 5.0651

>AT287939 WP_003839576.1 NZ_LR134485:c4287940-4287698 [Citrobacter youngae]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTVSDSEDTLIQTVRERLASPQKGIKVSLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0D7LMW6

Antitoxin

Source ID Structure
AlphaFold DB A0A0J1MV10

References