287933

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 1785287..1785877 Replicon chromosome
Accession NZ_LR134485
Organism Citrobacter youngae strain NCTC13709

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag EL296_RS08595 Protein ID WP_124022134.1
Coordinates 1785545..1785877 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag EL296_RS08590 Protein ID WP_079816675.1
Coordinates 1785287..1785544 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL296_RS08570 1782299..1783903 + 1605 WP_124022136.1 hypothetical protein -
EL296_RS24220 1783977..1784736 + 760 Protein_1636 ash family protein -
EL296_RS08580 1784733..1784939 + 207 WP_023187060.1 helix-turn-helix domain-containing protein -
EL296_RS08590 1785287..1785544 + 258 WP_079816675.1 antitoxin Antitoxin
EL296_RS08595 1785545..1785877 + 333 WP_124022134.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
EL296_RS08610 1786721..1787608 + 888 WP_124022132.1 integrase domain-containing protein -
EL296_RS08620 1788607..1789869 - 1263 WP_124022039.1 integrase arm-type DNA-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-109)

Antitoxin

Antitoxin PemI-like

(4-84)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11723.54 Da        Isoelectric Point: 10.1863

>T287933 WP_124022134.1 NZ_LR134485:1785545-1785877 [Citrobacter youngae]
MDRGEIWLVSLDPIAGHEQSGKRPVLIVSKASFNKLTQLPVVVPVTSGGNFARAAGFTVSLDGAGTKTTGVIRCDQPRTI
DMGARNGKRLERIPDAVVNEVLARLEAILS

Download         Length: 333 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9342.80 Da        Isoelectric Point: 4.4354

>AT287933 WP_079816675.1 NZ_LR134485:1785287-1785544 [Citrobacter youngae]
MYTTRLKKVGGSVMLAVPPAVLKTLGLSTDSDVGMTIDNGCLIIEPQKRPRYSLEELLAQCDPHAEMSEEDREWIDAPAV
GKEIL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References