Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 1124420..1125087 Replicon chromosome
Accession NZ_LR134485
Organism Citrobacter youngae strain NCTC13709

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag EL296_RS05510 Protein ID WP_057064441.1
Coordinates 1124420..1124749 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag EL296_RS05515 Protein ID WP_007870247.1
Coordinates 1124770..1125087 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL296_RS05495 1121078..1121536 - 459 WP_048212960.1 GNAT family N-acetyltransferase -
EL296_RS05500 1121663..1123131 + 1469 Protein_1047 PLP-dependent aminotransferase family protein -
EL296_RS05505 1123360..1124085 + 726 WP_121584942.1 GNAT family N-acetyltransferase -
EL296_RS05510 1124420..1124749 - 330 WP_057064441.1 TA system toxin CbtA family protein Toxin
EL296_RS05515 1124770..1125087 - 318 WP_007870247.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
EL296_RS05520 1125105..1125326 - 222 WP_001548165.1 DUF987 domain-containing protein -
EL296_RS05525 1125335..1125811 - 477 WP_057064440.1 RadC family protein -
EL296_RS05530 1125827..1126306 - 480 WP_081014411.1 antirestriction protein -
EL296_RS05535 1127160..1129355 - 2196 WP_124021032.1 DEAD/DEAH box helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1121663..1162814 41151
- inside Genomic island - - 1121663..1161514 39851


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-107)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12424.59 Da        Isoelectric Point: 10.1006

>T287932 WP_057064441.1 NZ_LR134485:c1124749-1124420 [Citrobacter youngae]
MKTLPATISRAAKPCLSPVAVWQMLLTRLLEKHYGLTLNDTPFWDQTVIKEHIDAGITLADAVNFLVDKYELVRIDRKGF
SWQEQTPYLSVVDILRARRSTGLLKAKVK

Download         Length: 330 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11839.44 Da        Isoelectric Point: 6.9459

>AT287932 WP_007870247.1 NZ_LR134485:c1125087-1124770 [Citrobacter youngae]
MNNTTWGLQRDITPRLGARLVQEGNRLHYLADRASITGKFSDAECLKLDVAFPHFISQMESMLTTGEMNPRHAHCVTLYH
NGFTCEADTLGSCGYVYIAIYPTQR

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References