Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 4726575..4727097 Replicon chromosome
Accession NZ_LR134478
Organism Serratia plymuthica strain NCTC8015

Toxin (Protein)


Gene name relE Uniprot ID A0A1B1KX47
Locus tag EL316_RS22605 Protein ID WP_006317109.1
Coordinates 4726575..4726856 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EL316_RS22610 Protein ID WP_119805097.1
Coordinates 4726846..4727097 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL316_RS22575 4721841..4722566 + 726 WP_006317106.1 LPS export ABC transporter ATP-binding protein -
EL316_RS22580 4722617..4724050 + 1434 WP_006317107.1 RNA polymerase factor sigma-54 -
EL316_RS22585 4724074..4724361 + 288 WP_126485505.1 ribosome hibernation promoting factor -
EL316_RS22590 4724644..4725105 + 462 WP_004948550.1 PTS IIA-like nitrogen regulatory protein PtsN -
EL316_RS22595 4725360..4726214 + 855 WP_004948553.1 RNase adapter RapZ -
EL316_RS22600 4726211..4726483 + 273 WP_004948556.1 PTS phosphocarrier protein NPr -
EL316_RS22605 4726575..4726856 - 282 WP_006317109.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL316_RS22610 4726846..4727097 - 252 WP_119805097.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
EL316_RS22615 4727204..4729120 - 1917 WP_126485507.1 BglG family transcription antiterminator -
EL316_RS22620 4729173..4730387 - 1215 WP_126528817.1 lactonase family protein -
EL316_RS22625 4730535..4731275 - 741 WP_126485511.1 KDGP aldolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10853.63 Da        Isoelectric Point: 10.6974

>T287920 WP_006317109.1 NZ_LR134478:c4726856-4726575 [Serratia plymuthica]
MSYNLKFEKRALKEWQKLGHPIREQLKKKLAERLENPHVPASRLSGRSNRYKIKLRSSGYRLVYEVNDTEVILLVIAVGK
RAGDEVYSIADKR

Download         Length: 282 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9178.25 Da        Isoelectric Point: 3.8308

>AT287920 WP_119805097.1 NZ_LR134478:c4727097-4726846 [Serratia plymuthica]
MTYQILTTTAASITDLKKNPMGTVADGDGGAVAILNRNEPAFYCVPPELYAYYRELAEDAELNRIADERMEDAEFVSVSL
DEL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B1KX47

Antitoxin

Source ID Structure

References