Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4315046..4315715 Replicon chromosome
Accession NZ_LR134478
Organism Serratia plymuthica strain NCTC8015

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag EL316_RS20655 Protein ID WP_126485007.1
Coordinates 4315046..4315468 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag EL316_RS20660 Protein ID WP_126485009.1
Coordinates 4315449..4315715 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL316_RS20635 4310068..4311431 + 1364 WP_126483961.1 IS3 family transposase -
EL316_RS20640 4311487..4312851 - 1365 WP_126485003.1 cell envelope integrity protein CreD -
EL316_RS20645 4312936..4314354 - 1419 WP_126528687.1 two-component system sensor histidine kinase CreC -
EL316_RS20650 4314351..4315046 - 696 WP_126528688.1 two-component system response regulator CreB -
EL316_RS20655 4315046..4315468 - 423 WP_126485007.1 protein YgfX Toxin
EL316_RS20660 4315449..4315715 - 267 WP_126485009.1 FAD assembly factor SdhE Antitoxin
EL316_RS20665 4316040..4317032 + 993 WP_126485011.1 tRNA-modifying protein YgfZ -
EL316_RS20670 4317118..4317795 - 678 WP_126485013.1 hemolysin III family protein -
EL316_RS20675 4317985..4318593 + 609 WP_126485015.1 HD domain-containing protein -
EL316_RS20680 4318635..4319570 - 936 WP_126485017.1 ribokinase -
EL316_RS20685 4319567..4320475 - 909 WP_172603410.1 allose kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16442.46 Da        Isoelectric Point: 10.4481

>T287918 WP_126485007.1 NZ_LR134478:c4315468-4315046 [Serratia plymuthica]
VAQWRCNVRISWRTQLLSLLTHGVLILLILIAPWPEGYGPIWLVMLTLVVFECIRSQKRIASLQGELRLLANKRLSWHGQ
EWLLVKQPWMPRYGILLTLQPIQGKKPRRLWLASDSMGKAEWRHLRQLLQYPSADDDEEP

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10474.95 Da        Isoelectric Point: 5.6062

>AT287918 WP_126485009.1 NZ_LR134478:c4315715-4315449 [Serratia plymuthica]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDRLNDTDKALFIRLLESDDPDLFNWLMNHGAPQDSELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References