Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3940408..3941063 Replicon chromosome
Accession NZ_LR134478
Organism Serratia plymuthica strain NCTC8015

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EL316_RS18910 Protein ID WP_126484530.1
Coordinates 3940408..3940797 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EL316_RS18915 Protein ID WP_126484532.1
Coordinates 3940800..3941063 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL316_RS18895 3936885..3938318 + 1434 WP_172603373.1 MFS transporter -
EL316_RS18900 3938315..3939697 + 1383 WP_126484528.1 two-component system sensor histidine kinase BaeS -
EL316_RS18905 3939697..3940413 + 717 WP_004951961.1 two-component system response regulator BaeR -
EL316_RS18910 3940408..3940797 - 390 WP_126484530.1 type II toxin-antitoxin system VapC family toxin Toxin
EL316_RS18915 3940800..3941063 - 264 WP_126484532.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
EL316_RS18920 3941414..3941752 + 339 WP_126484534.1 YegP family protein -
EL316_RS18925 3942055..3943407 + 1353 WP_126528572.1 tRNA 5-hydroxyuridine modification protein YegQ -
EL316_RS18930 3943900..3944799 + 900 WP_126528573.1 lipid kinase YegS -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-118)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14058.40 Da        Isoelectric Point: 7.8817

>T287915 WP_126484530.1 NZ_LR134478:c3940797-3940408 [Serratia plymuthica]
MYMFDTNTVSHLFRRHPGLLSAMEKVPPSTVCISSITEAELLFGVAKRQSKALKAMVTAFLAAVTVYDWDSEAARCYGVM
RASMEKKGKVLGALDQLIAAHALSRGATMVTSDRAFGMVPGLDVEDWTL

Download         Length: 390 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10158.46 Da        Isoelectric Point: 4.8950

>AT287915 WP_126484532.1 NZ_LR134478:c3941063-3940800 [Serratia plymuthica]
MERIAKLFKNGRNQAVRLPVEFEFDTDRVYIRRDREGNVILSKYPAKPDSWEPLLNMIAKTPVPHDFLGADERQQGIADR
DPFAEEE

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References