Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 3169894..3170537 Replicon chromosome
Accession NZ_LR134478
Organism Serratia plymuthica strain NCTC8015

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag EL316_RS15380 Protein ID WP_126483534.1
Coordinates 3169894..3170310 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag EL316_RS15385 Protein ID WP_126483536.1
Coordinates 3170307..3170537 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL316_RS15350 3165529..3165690 + 162 Protein_2958 IS1 family transposase -
EL316_RS15355 3166273..3166515 + 243 WP_126483528.1 acyl carrier protein -
EL316_RS15360 3166750..3166995 + 246 WP_126483530.1 transposase -
EL316_RS15365 3167050..3167364 - 315 Protein_2961 IS30 family transposase -
EL316_RS15380 3169894..3170310 - 417 WP_126483534.1 PIN domain-containing protein Toxin
EL316_RS15385 3170307..3170537 - 231 WP_126483536.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
EL316_RS15390 3171403..3171615 + 213 WP_126483538.1 hypothetical protein -
EL316_RS15395 3171959..3173803 - 1845 WP_126528294.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 3162909..3175817 12908


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-129)

Antitoxin

SpoVT-AbrB domain

(7-47)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15014.31 Da        Isoelectric Point: 8.5226

>T287913 WP_126483534.1 NZ_LR134478:c3170310-3169894 [Serratia plymuthica]
VNKTYMLDTNICSFIMREQPEAVIKRLEQAVLRNHRIVVSAITYAEMRFGAIGKKASPRHAQLVDAFCTRLDAVLAWDRA
AVDATTEIKAALAAAGTPIGPNDTAIAGHAIAAGAVLVTNNTREFERVPGLKQEDWVK

Download         Length: 417 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8731.78 Da        Isoelectric Point: 4.3654

>AT287913 WP_126483536.1 NZ_LR134478:c3170537-3170307 [Serratia plymuthica]
MRTVSIFKNGNNRAIRLPRDLDFEGVSELEIVREGDSIILRPVRPTWGSFAQFEKADADFMAEREDVVSDEGRFDL

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References