Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3131321..3131952 Replicon chromosome
Accession NZ_LR134478
Organism Serratia plymuthica strain NCTC8015

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EL316_RS15170 Protein ID WP_126528283.1
Coordinates 3131321..3131719 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EL316_RS15175 Protein ID WP_126483484.1
Coordinates 3131719..3131952 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL316_RS15145 3126839..3127225 + 387 WP_197718809.1 type II toxin-antitoxin system RelE/ParE family toxin -
EL316_RS15150 3127206..3127508 + 303 WP_126483474.1 transcriptional regulator -
EL316_RS15155 3127566..3127970 - 405 WP_126483476.1 flagellar protein FlhE -
EL316_RS15160 3127970..3130048 - 2079 WP_126483478.1 flagellar biosynthesis protein FlhA -
EL316_RS15165 3130041..3131192 - 1152 WP_126528282.1 flagellar type III secretion system protein FlhB -
EL316_RS15170 3131321..3131719 - 399 WP_126528283.1 type II toxin-antitoxin system VapC family toxin Toxin
EL316_RS15175 3131719..3131952 - 234 WP_126483484.1 antitoxin Antitoxin
EL316_RS15180 3132076..3132720 - 645 WP_126483486.1 protein phosphatase CheZ -
EL316_RS15185 3132731..3133120 - 390 WP_006321484.1 chemotaxis response regulator CheY -
EL316_RS15190 3133341..3134390 - 1050 WP_126483488.1 chemotaxis response regulator protein-glutamate methylesterase -
EL316_RS15195 3134390..3135262 - 873 WP_126483490.1 protein-glutamate O-methyltransferase CheR -
EL316_RS15200 3135291..3136916 - 1626 WP_126528284.1 Tar ligand binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

SpoVT-AbrB domain

(7-45)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14871.02 Da        Isoelectric Point: 7.5219

>T287912 WP_126528283.1 NZ_LR134478:c3131719-3131321 [Serratia plymuthica]
MFSHMLDTNIVIYVIKRRPIEVLSKFNQHAGKMVISSVTYAELIHGVEKSARPTENARVVDDFVSRLEILDYSAKAAAHY
GNIRASLEQQGTPMGVNDLHIAGHARSEGLVLVTNNLREFERVDGLRLQNWL

Download         Length: 399 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8851.89 Da        Isoelectric Point: 5.0642

>AT287912 WP_126483484.1 NZ_LR134478:c3131952-3131719 [Serratia plymuthica]
MTLGSVFTNNRTQAVRLPAEVRFPDSVSKVTVRVVGKERILAPVENTWDSFFCTDKHASDDFLTERAEQYQPERESF

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References