Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 1846589..1847353 Replicon chromosome
Accession NZ_LR134478
Organism Serratia plymuthica strain NCTC8015

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag EL316_RS08890 Protein ID WP_126527814.1
Coordinates 1846589..1846957 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag EL316_RS08895 Protein ID WP_126527815.1
Coordinates 1847018..1847353 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL316_RS08850 1841801..1841994 + 194 Protein_1693 hypothetical protein -
EL316_RS08855 1842404..1843372 + 969 WP_126481714.1 acyltransferase -
EL316_RS08860 1843491..1843769 + 279 WP_126527812.1 acylphosphatase -
EL316_RS08865 1843773..1844102 - 330 WP_004942823.1 sulfurtransferase TusE -
EL316_RS08870 1844214..1844873 - 660 WP_004942825.1 FtsH protease modulator YccA -
EL316_RS08880 1845332..1846165 - 834 WP_126527813.1 DUF4942 domain-containing protein -
EL316_RS08890 1846589..1846957 - 369 WP_126527814.1 TA system toxin CbtA family protein Toxin
EL316_RS08895 1847018..1847353 - 336 WP_126527815.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
EL316_RS08900 1847370..1847849 - 480 WP_126529012.1 DNA repair protein RadC -
EL316_RS08905 1847886..1848344 - 459 WP_126527816.1 antirestriction protein -
EL316_RS08910 1848526..1849749 - 1224 WP_172603401.1 O-antigen ligase family protein -
EL316_RS08915 1849835..1851004 - 1170 WP_126527818.1 putative lipopolysaccharide heptosyltransferase III -
EL316_RS08920 1851607..1852083 - 477 WP_126527819.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1828688..1856304 27616


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-111)

Antitoxin

Antitoxin CbeA

(7-107)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13902.05 Da        Isoelectric Point: 8.2684

>T287906 WP_126527814.1 NZ_LR134478:c1846957-1846589 [Serratia plymuthica]
MKTSPFPPKREVYSCPSPVAIWRDLLTYLLAQHYGLTVNDTVFSDDTIIQEHIEAGISLADALNFIVEKFDLVRIDRRGF
SCREQSPFVTVIDILRARQACGLMSRRGYRAITQTILGDKRP

Download         Length: 369 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12492.14 Da        Isoelectric Point: 7.0470

>AT287906 WP_126527815.1 NZ_LR134478:c1847353-1847018 [Serratia plymuthica]
MTSINTPAWGLKRNVTPQFGARLVQQGNHLHYLADRAGISGTFSEVQTRHLDEAFPQFINHLELMLLSGELNPRYQHCVT
LYRNGLTCEADSLGSHGYVYISVYPTQMPVT

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References