287905

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1706607..1707132 Replicon chromosome
Accession NZ_LR134478
Organism Serratia plymuthica strain NCTC8015

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EL316_RS08265 Protein ID WP_062792950.1
Coordinates 1706607..1706891 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1B1KNT6
Locus tag EL316_RS08270 Protein ID WP_006320890.1
Coordinates 1706881..1707132 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL316_RS08240 1701871..1703004 + 1134 WP_126481543.1 putrescine ABC transporter ATP-binding subunit PotG -
EL316_RS08245 1703035..1703988 + 954 WP_126529010.1 putrescine ABC transporter permease PotH -
EL316_RS08250 1703985..1704830 + 846 WP_006320894.1 putrescine ABC transporter permease PotI -
EL316_RS08255 1704933..1705412 + 480 WP_126481545.1 DUF2593 family protein -
EL316_RS08260 1705483..1706610 + 1128 WP_126527786.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
EL316_RS08265 1706607..1706891 - 285 WP_062792950.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL316_RS08270 1706881..1707132 - 252 WP_006320890.1 prevent-host-death protein Antitoxin
EL316_RS08275 1707244..1707978 - 735 WP_126481547.1 arginine ABC transporter substrate-binding protein -
EL316_RS08280 1708183..1708851 - 669 WP_126527787.1 arginine ABC transporter permease ArtM -
EL316_RS08285 1708851..1709567 - 717 WP_013812256.1 arginine ABC transporter permease ArtQ -
EL316_RS08290 1709577..1710308 - 732 WP_013812257.1 arginine ABC transporter substrate-binding protein -
EL316_RS08295 1710342..1711070 - 729 WP_126527788.1 arginine ABC transporter ATP-binding protein ArtP -
EL316_RS08300 1711326..1711874 - 549 WP_126481553.1 lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10832.80 Da        Isoelectric Point: 10.0293

>T287905 WP_062792950.1 NZ_LR134478:c1706891-1706607 [Serratia plymuthica]
MTYSLEFEEHALKEFKKLAPVLRDQFKKKLATVLENPCIPANRLSGLSDCYKIKLKASGYRLVYRVIDEEIVVLVLSIGK
RERSEAYTAAKKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9095.44 Da        Isoelectric Point: 6.2821

>AT287905 WP_006320890.1 NZ_LR134478:c1707132-1706881 [Serratia plymuthica]
MIVQPILANSAVSISDFKKSPNTALKEANGQPVAVLTNGKISGYYVSPETWEAISEYLEDIELAKIARSRMSGKRIKVNL
DDL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1B1KNT6

References