Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 1995728..1996233 Replicon chromosome
Accession NZ_LR134477
Organism Actinomyces viscosus strain NCTC10951

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag EL340_RS08545 Protein ID WP_126414250.1
Coordinates 1995728..1995982 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EL340_RS08550 Protein ID WP_126414251.1
Coordinates 1995982..1996233 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL340_RS08530 1992013..1992522 - 510 WP_126414248.1 DUF1877 domain-containing protein -
EL340_RS08535 1993026..1995407 + 2382 WP_126414249.1 exo-alpha-sialidase -
EL340_RS08545 1995728..1995982 - 255 WP_126414250.1 Txe/YoeB family addiction module toxin Toxin
EL340_RS08550 1995982..1996233 - 252 WP_126414251.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
EL340_RS08555 1996974..2000828 + 3855 WP_164719363.1 peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1995728..2004174 8446


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9812.20 Da        Isoelectric Point: 9.7867

>T287899 WP_126414250.1 NZ_LR134477:c1995982-1995728 [Actinomyces viscosus]
MRLVWDPSAWEDYKHWQTTDRRVLKRVNTLIGAALRDPFGGIGKPEQLKYGASGAWSRRISDEHRLVYLVVGDDLVILQA
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9479.48 Da        Isoelectric Point: 4.6533

>AT287899 WP_126414251.1 NZ_LR134477:c1996233-1995982 [Actinomyces viscosus]
VSISASEARKTLYPLIERVNADHDAVEIVSRKGAVVLMPADEYAAWQETAYLFRSPENARRLLDAYDRARSGRTETHDLD
WED

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References