Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 1995728..1996233 Replicon chromosome
Accession NZ_LR134477
Organism Actinomyces viscosus strain NCTC10951

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag EL340_RS08545 Protein ID WP_126414250.1
Coordinates 1995728..1995982 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EL340_RS08550 Protein ID WP_126414251.1
Coordinates 1995982..1996233 (-) Length 84 a.a.

Genomic Context


EL340_RS08535EL340_RS08555EL340_RS08530EL340_RS08545EL340_RS08550
Location: 1993026..1995407 (2382 bp)
Type: Others
Protein ID: WP_126414249.1
Location: 1996974..2000828 (3855 bp)
Type: Others
Protein ID: WP_164719363.1
Location: 1992013..1992522 (510 bp)
Type: Others
Protein ID: WP_126414248.1
Location: 1995728..1995982 (255 bp)
Type: Toxin
Protein ID: WP_126414250.1
Location: 1995982..1996233 (252 bp)
Type: Antitoxin
Protein ID: WP_126414251.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EL340_RS085301992013..1992522-510WP_126414248.1DUF1877 domain-containing protein-
EL340_RS085351993026..1995407+2382WP_126414249.1exo-alpha-sialidase-
EL340_RS085451995728..1995982-255WP_126414250.1Txe/YoeB family addiction module toxinToxin
EL340_RS085501995982..1996233-252WP_126414251.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
EL340_RS085551996974..2000828+3855WP_164719363.1peptidase-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--1995728..20041748446


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-84)

Antitoxin

(2-68)


Sequences


Toxin        


Download         Length: 85 a.a.        Molecular weight: 9812.20 Da        Isoelectric Point: 9.7867

>T287899 WP_126414250.1 NZ_LR134477:c1995982-1995728 [Actinomyces viscosus]
MRLVWDPSAWEDYKHWQTTDRRVLKRVNTLIGAALRDPFGGIGKPEQLKYGASGAWSRRISDEHRLVYLVVGDDLVILQA
RYHY

Download         Length: 255 bp


Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9479.48 Da        Isoelectric Point: 4.6533

>AT287899 WP_126414251.1 NZ_LR134477:c1996233-1995982 [Actinomyces viscosus]
VSISASEARKTLYPLIERVNADHDAVEIVSRKGAVVLMPADEYAAWQETAYLFRSPENARRLLDAYDRARSGRTETHDLD
WED

Download         Length: 252 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References