Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 20391..21025 Replicon plasmid 17
Accession NZ_LR134459
Organism Tsukamurella tyrosinosolvens strain NCTC13231

Toxin (Protein)


Gene name vapC Uniprot ID A0A1H4Q0Z2
Locus tag EL451_RS14125 Protein ID WP_068741167.1
Coordinates 20391..20810 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EL451_RS14130 Protein ID WP_068524620.1
Coordinates 20807..21025 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL451_RS14110 16240..16455 - 216 WP_074850442.1 hypothetical protein -
EL451_RS14115 16546..19179 - 2634 WP_068741168.1 AAA family ATPase -
EL451_RS14120 19176..20312 - 1137 WP_068741253.1 exonuclease SbcCD subunit D -
EL451_RS14125 20391..20810 - 420 WP_068741167.1 ribonuclease Toxin
EL451_RS14130 20807..21025 - 219 WP_068524620.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
EL451_RS14135 21084..21869 - 786 WP_068524619.1 hypothetical protein -
EL451_RS14140 21870..24749 - 2880 WP_068741166.1 DEAD/DEAH box helicase -
EL451_RS14145 24752..25375 - 624 WP_068524617.1 GNAT family N-acetyltransferase -
EL451_RS14150 25386..25934 - 549 WP_082791318.1 thioesterase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..238675 238675


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 20622.74 Da        Isoelectric Point: 5.5500

>T287888 WP_068741167.1 NZ_LR134459:c20810-20391 [Tsukamurella tyrosinosolvens]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Download         Length: 420 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 10761.91 Da        Isoelectric Point: 5.5500

>AT287888 WP_068524620.1 NZ_LR134459:c21025-20807 [Tsukamurella tyrosinosolvens]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1H4Q0Z2

Antitoxin

Source ID Structure

References