287885

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE-HTH
Location 2658695..2659233 Replicon chromosome
Accession NZ_LR134442
Organism Propionibacterium australiense strain NCTC13651

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EL282_RS11770 Protein ID WP_119162610.1
Coordinates 2658695..2658961 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag EL282_RS11775 Protein ID WP_119162609.1
Coordinates 2658961..2659233 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL282_RS11755 2654972..2655898 + 927 WP_119162613.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
EL282_RS11760 2656171..2657619 + 1449 WP_119162612.1 amino acid permease -
EL282_RS11765 2657623..2658615 + 993 WP_119162611.1 asparaginase -
EL282_RS11770 2658695..2658961 - 267 WP_119162610.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL282_RS11775 2658961..2659233 - 273 WP_119162609.1 ribbon-helix-helix protein, CopG family Antitoxin
EL282_RS11780 2659365..2660012 - 648 WP_119162608.1 class II aldolase/adducin family protein -
EL282_RS11785 2660028..2661947 - 1920 WP_119162607.1 PTS sugar transporter subunit IIA -
EL282_RS11790 2662207..2663265 + 1059 WP_119162606.1 alcohol dehydrogenase catalytic domain-containing protein -
EL282_RS11795 2663270..2663569 + 300 WP_119162605.1 PTS sugar transporter subunit IIB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin

Protein of unknown function DUF6290

(4-72)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10010.70 Da        Isoelectric Point: 11.0068

>T287885 WP_119162610.1 NZ_LR134442:c2658961-2658695 [Propionibacterium australiense]
MAWTLRFSSDFERSLHKLDRQTARRILVKLHGLVSLDEPQARCKGLAGPLAGLWRLRVGDYRVLLDIRRAELVIVALGVG
HRSSIYDT

Download         Length: 267 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9998.99 Da        Isoelectric Point: 4.2800

>AT287885 WP_119162609.1 NZ_LR134442:c2659233-2658961 [Propionibacterium australiense]
MSTSVLSIRLPDEVKNRLDALSASTGRPAAFYVREAVLEHLDELEWAYSLAARAEAIRNGTEETRSFDEVARGLGFDPDE
LRAEASEDRS

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References