287884

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 2093794..2094346 Replicon chromosome
Accession NZ_LR134442
Organism Propionibacterium australiense strain NCTC13651

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag EL282_RS09245 Protein ID WP_119161073.1
Coordinates 2093794..2094111 (-) Length 106 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag EL282_RS09250 Protein ID WP_119161072.1
Coordinates 2094113..2094346 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL282_RS09230 2089100..2092144 - 3045 WP_119161075.1 excinuclease ABC subunit UvrA -
EL282_RS09235 2092431..2093180 + 750 WP_119161074.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
EL282_RS09240 2093183..2093779 + 597 WP_119161143.1 MBL fold metallo-hydrolase -
EL282_RS09245 2093794..2094111 - 318 WP_119161073.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
EL282_RS09250 2094113..2094346 - 234 WP_119161072.1 ribbon-helix-helix domain-containing protein Antitoxin
EL282_RS09255 2094434..2095483 - 1050 WP_119161071.1 TerC/Alx family metal homeostasis membrane protein -
EL282_RS09260 2095711..2097789 - 2079 WP_119161070.1 excinuclease ABC subunit UvrB -
EL282_RS09265 2097872..2098534 + 663 WP_126464245.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-87)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11259.99 Da        Isoelectric Point: 4.4678

>T287884 WP_119161073.1 NZ_LR134442:c2094111-2093794 [Propionibacterium australiense]
VREICLAEFDKTRPVLVLTRELAREAMTKVTVAPITSTVKGLSSELRLGPDNGLDHECAASLDNVVTIPVTSLGRTVGFL
GPDQERALAVAVVLAYDLQVSLLED

Download         Length: 318 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8211.18 Da        Isoelectric Point: 4.0932

>AT287884 WP_119161072.1 NZ_LR134442:c2094346-2094113 [Propionibacterium australiense]
MSVQITVRLPGELVSFLDDSVAEGRAQSRAALVASALEREMRRQAAITDARILAEQGPGDDLDALVSWSVSNAALED

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References