287883

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1433467..1434080 Replicon chromosome
Accession NZ_LR134442
Organism Propionibacterium australiense strain NCTC13651

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EL282_RS06320 Protein ID WP_119160674.1
Coordinates 1433697..1434080 (+) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EL282_RS06315 Protein ID WP_119160675.1
Coordinates 1433467..1433697 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL282_RS06300 1430340..1431908 + 1569 WP_119160678.1 sodium-dependent transporter -
EL282_RS06305 1431910..1432017 + 108 WP_119160677.1 MetS family NSS transporter small subunit -
EL282_RS06310 1432130..1433227 - 1098 WP_119160676.1 DUF418 domain-containing protein -
EL282_RS06315 1433467..1433697 + 231 WP_119160675.1 toxin-antitoxin system, antitoxin component Antitoxin
EL282_RS06320 1433697..1434080 + 384 WP_119160674.1 type II toxin-antitoxin system VapC family toxin Toxin
EL282_RS06325 1434184..1434987 + 804 WP_119160673.1 MerR family transcriptional regulator -
EL282_RS06330 1435161..1435400 - 240 WP_119160672.1 type B 50S ribosomal protein L31 -
EL282_RS06335 1435470..1435706 + 237 WP_119160671.1 50S ribosomal protein L28 -
EL282_RS06340 1435706..1435879 + 174 WP_119160670.1 50S ribosomal protein L33 -
EL282_RS06345 1436014..1436913 - 900 WP_119160669.1 family 1 glycosylhydrolase -
EL282_RS06350 1437065..1437829 + 765 WP_197720667.1 transposase -
EL282_RS06355 1437792..1438355 - 564 WP_197720668.1 glycoside hydrolase family 1 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Pae0151-like, PIN domain

(3-125)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 13560.59 Da        Isoelectric Point: 4.3711

>T287883 WP_119160674.1 NZ_LR134442:1433697-1434080 [Propionibacterium australiense]
MWVIDASAAAELLLGTTQGRAVAATIGDEDVYAPQLLAVEVVSVMRGMVRGGDITGTRAEAALHDFDDLGVIWVDMSPLI
SAAWALRDSASAHDAMYVALAERLECPLLTCDRRLAKTFTRCVVPQG

Download         Length: 384 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8832.98 Da        Isoelectric Point: 9.9557

>AT287883 WP_119160675.1 NZ_LR134442:1433467-1433697 [Propionibacterium australiense]
MSTVQIRNVPDELSRELKARAAREGRSLSDYLLRELERVASRPSRAELYERIQGRDPGSELPPASEVLERERMRRP

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References