287879

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 10481..11157 Replicon chromosome
Accession NZ_LR134442
Organism Propionibacterium australiense strain NCTC13651

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EL282_RS00035 Protein ID WP_119162416.1
Coordinates 10720..11157 (+) Length 146 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EL282_RS00030 Protein ID WP_119162415.1
Coordinates 10481..10714 (+) Length 78 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL282_RS00025 8270..9898 - 1629 WP_119162414.1 NAD(P)-binding protein -
EL282_RS00030 10481..10714 + 234 WP_119162415.1 DUF2191 domain-containing protein Antitoxin
EL282_RS00035 10720..11157 + 438 WP_119162416.1 VapC toxin family PIN domain ribonuclease Toxin
EL282_RS00040 11204..11512 - 309 WP_119162417.1 thiamine-binding protein -
EL282_RS00045 11652..12242 + 591 WP_119162418.1 DUF1440 domain-containing protein -
EL282_RS13755 12264..14078 - 1815 WP_197720674.1 thiol reductant ABC exporter subunit CydC -
EL282_RS13760 14055..15671 - 1617 Protein_10 thiol reductant ABC exporter subunit CydD -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(8-126)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 146 a.a.        Molecular weight: 15990.32 Da        Isoelectric Point: 5.7720

>T287879 WP_119162416.1 NZ_LR134442:10720-11157 [Propionibacterium australiense]
MTQHRTRLLDVNVVIALSLPSHVHHEIVTTWFEDVRDWATCPITQSAYVRLLLNQNVTGFRIAPGDVLAGMAALCAVDGH
EFLSDDAPLSEPLIDFSVLSGSKQVTDLHLVDLAARHRAVLATMDSRIPNALAPDDRRHVELIPV

Download         Length: 438 bp


Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8360.50 Da        Isoelectric Point: 6.4625

>AT287879 WP_119162415.1 NZ_LR134442:10481-10714 [Propionibacterium australiense]
MRTTLDLDDKVLAVARERARREGISLGRAVSQLALLGITGISFKTGSRGVPLFTPPPGSSPHPVTPELIEQHRDEDE

Download         Length: 234 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References